Effects of date extract on adhesion of Candida species to human buccal epithelial cells in vitro

被引:16
作者
Abu-Elteen, KH [1 ]
机构
[1] Hashemite Univ, Fac Sci, Dept Biol Sci, Zarqa 13115, Jordan
关键词
adhesion; Candida species; date extract; mouth;
D O I
10.1034/j.1600-0714.2000.290502.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The adherence of three Candida species to human buccal epithelial cells (BEC) following treatment with different concentrations of date extract was investigated in vitro, as well as the effect of a mouth rinse with date extract on the adhesion of yeast to BEC. Adhesion of C. albicans, C.tropicalis and C.kefyr to BEC was significantly reduced after both short- and long-term periods of yeast exposure to various concentrations of date extract (reduction between 25% and 52% of the control value). A similar inhibition of adherence was observed upon pre-incubation of BEC with date extract. There was a significant reduction (P<0.001) in the adherence of yeast to BEC collected immediately or 5-20 min after an oral rinse with 10% date extract. No statistically significant difference was observed in the adhesion of BEC collected 30 min after an oral rinse with date extract and control BEC. In addition, pre-treatment of either Candida or BEC, or both, with date extract resulted in reduced adherence, the magnitude of which was largest when both types of cells were pre-treated. Date extract also inhibited germ-tube formation of C. albicans (56-85% inhibition), which might contribute to the effects on adherence.
引用
收藏
页码:200 / 205
页数:6
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