The spliceosome as ribozyme hypothesis takes a second step

被引：9
作者：
Butcher, Samuel E. [1 ]
机构：
[1] Univ Wisconsin, Dept Biochem, Madison, WI 53706 USA
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2009年 / 106卷 / 30期
关键词：
CRYSTAL-STRUCTURE; CATALYSIS; DOMAIN; PRP8; 1ST-STEP; REVEALS; HEART;
D O I：
10.1073/pnas.0906762106
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：12211 / 12212
页数：2
相关论文
共 31 条
[1]   Is the spliceosome a ribonucleoprotein enzyme? [J].
Abelson, John .
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2008, 15 (12) :1235-1237
[2]   ISOLATION OF NEW RIBOZYMES FROM A LARGE POOL OF RANDOM SEQUENCES [J].
BARTEL, DP ;
SZOSTAK, JW .
SCIENCE, 1993, 261 (5127) :1411-1418
[3]   Allosteric cascade of spliceosome activation [J].
Brow, DA .
ANNUAL REVIEW OF GENETICS, 2002, 36 :333-360
[4]   Structural biology - The ribosome is a ribozyme [J].
Cech, TR .
SCIENCE, 2000, 289 (5481) :878-879
[5]  
Collins CA, 2000, NAT STRUCT BIOL, V7, P850
[6]   Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: Extending the parallels between the spliceosome and group II introns [J].
Gordon, PM ;
Sontheimer, EJ ;
Piccirilli, JA .
RNA, 2000, 6 (02) :199-205
[7]   Metal binding and base ionization in the U6 RNA intramolecular stem-loop structure [J].
Huppler, A ;
Nikstad, LJ ;
Allmann, AM ;
Brow, DA ;
Butcher, SE .
NATURE STRUCTURAL BIOLOGY, 2002, 9 (06) :431-435
[8]   Three-dimensional structure of C complex spliceosomes by electron microscopy [J].
Jurica, MS ;
Sousa, D ;
Moore, MJ ;
Grigorieff, N .
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2004, 11 (03) :265-269
[9]   Pre-mRNA splicing: Awash in a sea of proteins [J].
Jurica, MS ;
Moore, MJ .
MOLECULAR CELL, 2003, 12 (01) :5-14
[10]   Structural mapping of spliceosomes by electron microscopy [J].
Luehrmann, Reinhard ;
Stark, Holger .
CURRENT OPINION IN STRUCTURAL BIOLOGY, 2009, 19 (01) :96-102
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