Relation between leptin and the regulation of glucose metabolism

被引：115
作者：
Frühbeck, G [1 ]
Salvador, J [1 ]
机构：
[1] Univ Navarra, Dept Endocrinol, Univ Clin, Pamplona 31008, Spain
来源：
DIABETOLOGIA | 2000年 / 43卷 / 01期
关键词：
leptin; ob gene; insulin; glucagon; cholecystokinin; glucose homeostasis; obesity; satiety;
D O I：
10.1007/s001250050002
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：3 / 12
页数：10
相关论文
共 92 条
[71]   Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice [J].
Schwartz, MW ;
Baskin, DG ;
Bukowski, TR ;
Kuijper, JL ;
Foster, D ;
Lasser, G ;
Prunkard, DE ;
Porte, D ;
Woods, SC ;
Seeley, RJ ;
Weigle, DS .
DIABETES, 1996, 45 (04) :531-535
[72]   Leptin suppression of insulin secretion and gene expression in human pancreatic islets: Implications for the development of adipogenic diabetes mellitus [J].
Seufert, J ;
Kieffer, TJ ;
Leech, CA ;
Holz, GG ;
Moritz, W ;
Ricordi, C ;
Habener, JF .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (02) :670-676
[73]   Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice [J].
Seufert, J ;
Kieffer, TJ ;
Habener, JF .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (02) :674-679
[74]   Direct antidiabetic effect of leptin through triglyceride depletion of tissues [J].
Shimabukuro, M ;
Koyama, K ;
Chen, GX ;
Wang, MY ;
Trieu, F ;
Lee, Y ;
Newgard, CB ;
Unger, RH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (09) :4637-4641
[75]   Biological action of leptin as an angiogenic factor [J].
Sierra-Honigmann, MR ;
Nath, AK ;
Murakami, C ;
García-Cardeña, G ;
Papapetropoulos, A ;
Sessa, WC ;
Madge, LA ;
Schechner, JS ;
Schwabb, MB ;
Polverini, PJ ;
Flores-Riveros, JR .
SCIENCE, 1998, 281 (5383) :1683-1686
[76]   Effects of leptin on insulin sensitivity in normal rats [J].
Sivitz, WI ;
Walsh, SA ;
Morgan, DA ;
Thomas, MJ ;
Haynes, WG .
ENDOCRINOLOGY, 1997, 138 (08) :3395-3401
[77]   Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels [J].
Spanswick, D ;
Smith, MA ;
Groppi, VE ;
Logan, SD ;
Ashford, MLJ .
NATURE, 1997, 390 (6659) :521-525
[78]   Leptin induces mitogen-activated protein kinase-dependent proliferation of C3H10T1/2 cells [J].
Takahashi, Y ;
Okimura, Y ;
Mizuno, I ;
Iida, K ;
Takahashi, T ;
Kaji, H ;
Abe, H ;
Chihara, K .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (20) :12897-12900
[79]   The leptin receptor [J].
Tartaglia, LA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (10) :6093-6096
[80]   Leptin: Fundamental aspects [J].
Trayhurn P. ;
Hoggard N. ;
Mercer J.G. ;
Rayner D.V. .
International Journal of Obesity, 1999, 23 (Suppl 1) :22-28
12345678910