Design of a Dual Slot Antenna for Small Animal Microwave Ablation Studies

被引：0

作者：

Moon, Tyler J.

Brace, Christopher L.

机构：

来源：

2016 38TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) | 2016年

关键词：

Microwave ablation; radiofrequency ablation; small animal model; RADIOFREQUENCY ABLATION; HEPATOCELLULAR-CARCINOMA; EX-VIVO; VALIDATION; RESECTION; TISSUE; TUMORS;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

This study presents the development of a dual-slot antenna for small animal tumor ablation. By using a dual-slot design at 8 GHz, it was hypothesized that smaller and more spherical ablations can be produced. After computer-aided design optimization, antennas were fabricated and ablations performed at 5-20 W for 15-120 s with the objective of creating ablations with a diameter/length aspect ratio of at least 0.9. The new dual-slot design at 8 GHz created significantly more spherical ablations than a commercial antenna at 2.45 GHz in ex vivo liver tissue (Average Aspect Ratio 0.8081 vs. 0.4532, p << 0.05). In vivo studies confirmed the highly spherical results ex vivo. Initial testing shows that the dual-slot antenna and 8 GHz generator can be used to ablate tumors in mice.

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页码：348 / 351

页数：4

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