SYNTHESIS OF SMALL PEPTIDE INHIBITORS TO THE POLO-BOX DOMAIN OF POLO-LIKE KINASE 1

被引:0
作者
Ahn, M. [1 ]
Park, J. -E. [2 ]
Lee, K. S. [2 ]
Shin, S. Y. [3 ,4 ]
Bang, J. K. [1 ]
机构
[1] Korea Basic Sci Inst, Div Magnet Resonance, Ochang 363883, Chung Buk, South Korea
[2] NCI, Lab Metab, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
[3] Chosun Univ, Grad Sch, Dept Biomat, Kwangju 501759, South Korea
[4] Chosun Univ, Sch Med, Dept Cellular & Mol Med, Kwangju 501759, South Korea
关键词
polo-like kinase 1 (Plk1); polo-box domain (PBD); peptide inhibitor; solid phase peptide synthesis; anticancer therapeutic agent;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
P070
引用
收藏
页码:S155 / S155
页数:1
相关论文
共 4 条
  • [1] Polo-like kinases and oncogenesis
    Eckerdt, F
    Yuan, JP
    Strebhardt, K
    [J]. ONCOGENE, 2005, 24 (02) : 267 - 276
  • [2] Pinning down the polo-box domain
    Lee, Kyung S.
    Idle, Jeffrey R.
    [J]. CHEMISTRY & BIOLOGY, 2008, 15 (05): : 415 - 416
  • [3] Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides Using Oxime-Based Diversification
    Liu, Fa
    Park, Jung-Eun
    Qian, Wen-Jian
    Lim, Dan
    Scharow, Andrej
    Berg, Thorsten
    Yaffe, Michael B.
    Lee, Kyung S.
    Burke, Terrence R., Jr.
    [J]. ACS CHEMICAL BIOLOGY, 2012, 7 (05) : 805 - 810
  • [4] Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1
    Yun, Sang-Moon
    Moulaei, Tinoush
    Lim, Dan
    Bang, Jeong K.
    Park, Jung-Eun
    Shenoy, Shilpa R.
    Liu, Fa
    Kang, Young H.
    Liao, Chenzhong
    Soung, Nak-Kyun
    Lee, Sunhee
    Yoon, Do-Young
    Lim, Yoongho
    Lee, Dong-Hee
    Otaka, Akira
    Appella, Ettore
    McMahon, James B.
    Nicklaus, Marc C.
    Burke, Terrence R., Jr.
    Yaffe, Michael B.
    Wlodawer, Alexander
    Lee, Kyung S.
    [J]. NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2009, 16 (08) : 876 - U104