The Influence of Various Patient Characteristics on D-dimer Concentration in Critically Ill Patients and Its Role as a Prognostic Indicator in the Intensive Care Unit Setting

被引：27

作者：

Spring, Jenna L. ^{[1
]}

Winkler, Anne ^{[2
]}

Levy, Jerrold H. ^{[3
,4
]}

机构：

[1] Univ Toronto, Dept Med, Toronto, ON M5G 2C4, Canada

[2] Emory Univ, Dept Pathol, Atlanta, GA 30322 USA

[3] Duke Univ, Sch Med, Div Cardiothorac Anesthesiol, Duke Univ Hosp, Durham, NC 27710 USA

[4] Duke Univ, Sch Med, Div Crit Care, Duke Univ Hosp, Durham, NC 27710 USA

来源：

CLINICS IN LABORATORY MEDICINE | 2014年 / 34卷 / 03期

关键词：

Bleeding; Safety; D-dimer; Disseminated intravascular coagulation; Intensive care unit; In-hospital mortality; PLASMA D-DIMER; DISSEMINATED INTRAVASCULAR COAGULATION; CKD-EPI EQUATION; VENOUS THROMBOEMBOLISM; FIBRIN; MORTALITY; ASSAY; AGE; EPIDEMIOLOGY; EXCLUSION;

D O I：

10.1016/j.cll.2014.06.015

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

This study examines the relationship between D-dimer concentration and patient age, gender, race, and renal function, and the role of D-dimer concentration as a predictor of in-hospital mortality, in a critically ill patient population. The results demonstrate there is a correlation between increased D-dimer concentration and renal impairment in critically ill patients, with patients in renal failure having the highest D-dimer concentrations. Peak D-dimer levels were higher among female patients than in male patients, but there was no association between peak D-dimer levels and other patient characteristics. D-dimer concentration was also not predictive of in-hospital mortality.

引用

页码：675 / +

页数：14

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