Limbic encephalitis - a review

被引：70

作者：

Anderson, N. E. ^{[1
]}

Barber, P. A. ^{[1
]}

机构：

[1] Auckland City Hosp, Dept Neurol, Auckland, New Zealand

来源：

JOURNAL OF CLINICAL NEUROSCIENCE | 2008年 / 15卷 / 09期

关键词：

Autoantibodies; Limbic encephalitis; Paraneoplastic syndromes;

D O I：

10.1016/j.jocn.2007.12.003

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The clinical features of limbic encephalitis are diverse and early diagnosis of the disorder is frequently difficult. Four patients with limbic encephalitis are described. An antineuronal antibody was identified in three of these patients. Antibodies directed against voltage-gated potassium channels, the N-methyl-D-aspartate receptor and an unidentified neuropil antigen were each found in one patient. The fourth patient had multifocal paraneoplastic encephalitis associated with small cell lung cancer. The clinical and imaging findings associated with these antibodies and the other antineuronal antibodies described in patients with limbic encephalitis are reviewed. An approach to the diagnosis and management of limbic encephalitis is presented. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：961 / 971

页数：11

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