Ratiometric and Time-Resolved Fluorimetry from Quantum Dots Featuring Drug Carriers for Real-Time Monitoring of Drug Release in Situ

被引:45
|
作者
Gui, Rijun [1 ,2 ]
Wan, Ajun [2 ,3 ]
Zhang, Yalei [3 ]
Li, Huili [1 ]
Zhao, Tingting [2 ]
机构
[1] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, Dept Chem, Shanghai 200240, Peoples R China
[3] Tongji Univ, Natl Engn Res Ctr Facil Agr, State Key Lab Pollut Control & Resources Reuse, Shanghai 200092, Peoples R China
基金
中国国家自然科学基金;
关键词
RESONANCE ENERGY-TRANSFER; MESOPOROUS SILICA NANOPARTICLES; FLUORESCENCE DETECTION; CARBON NANOTUBES; DELIVERY; PH; FRET; DOXORUBICIN; NANOSENSOR; BIOSENSORS;
D O I
10.1021/ac501293e
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
An effective ratiometric and time-resolved fluorimetry was described. On the basis of Forster resonance energy transfer (FRET) between semiconductor quantum dots (QDs) and fluorescent drugs, poly(ethylene glycol)-modified QDs were successfully prepared and further developed as QDs featuring carriers for real-time monitoring of drug release in situ.
引用
收藏
页码:5211 / 5214
页数:4
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