Report from the Eleventh Killer Immunoglobulin-like Receptor (KIR) Workshop: Novel insights on KIR polymorphism, ligand recognition, expression and function

被引：3

作者：

Falco, Michela ^{[1
]}

Sivori, Simona ^{[2
,3
]}

Meazza, Raffaella ^{[4
]}

Pende, Daniela ^{[4
]}

机构：

[1] IRCCS Ist G Gaslini, Lab Immunol Clin & Sperimentale, Genoa, Italy

[2] Univ Genoa, Dipartimento Med Sperimentale DIMES, Genoa, Italy

[3] Univ Genoa, Ctr Eccellenza Ric Biomed CEBR, Genoa, Italy

[4] IRCCS Osped Policlin San Martino, Lab Immunol, Largo R Beni 10, I-16132 Genoa, Italy

来源：

HLA | 2019年 / 94卷 / 02期

关键词：

HLA class I; killer cell immunoglobulin-like receptors (KIR); KIR/KIR-ligand interaction; natural killer (NK) cells; polymorphism; HLA-C; LEUKEMIA RELAPSE; CELL; DIVERSITY; MOLECULES; GENOTYPES;

D O I：

10.1111/tan.13608

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The Eleventh Killer Immunoglobulin-like Receptor (KIR) Workshop was held in Camogli (Genoa, Italy) in October 2018. This congress brought together 113 participants working on KIR field. Fifty-eight studies have been presented, the majority of which included unpublished data. Thus, KIR workshop, allowing the meeting of people sharing their knowledge and experience in a friendly atmosphere, still represents a special event of fruitful discussion and exchange of novel breakthrough, results, and ideas. In this report, we summarize all the scientific contributions highlighting the most recent advances in KIR field. Forty abstracts presented at the KIR Workshop are published in this issue.

引用

页码：100 / 110

页数：11

共 49 条

[1] Dual redundant sequencing strategy: Full-length gene characterisation of 1056 novel and confirmatory HLA alleles [J].

Albrecht, V. ;

Zweiniger, C. ;

Surendranath, V. ;

Lang, K. ;

Schoefl, G. ;

Dahl, A. ;

Winkler, S. ;

Lange, V. ;

Boehme, I. ;

Schmidt, A. H. .

HLA, 2017, 90 (02) :79-87

[2] Presence of centromeric but absence of telomeric group B KIR haplotypes in stem cell donors improve leukaemia control after HSCT for childhood ALL [J].

Babor, Florian ;

Peters, Christina ;

Manser, Angela R. ;

Glogova, Evgenia ;

Sauer, Martin ;

Poetschger, Ulrike ;

Ahlmann, Martina ;

Cario, Gunnar ;

Feuchtinger, Tobias ;

Gruhn, Bernd ;

Gungor, Tayfun ;

Horn, Peter A. ;

Kremens, Bernhard ;

Lang, Peter ;

Mezger, Markus ;

Mueller, Ingo ;

Mytilineos, Joannis ;

Oevermann, Lena ;

Pichler, Herbert ;

Scherenschlich, Nadine ;

Schuster, Friedhelm R. ;

Siepermann, Meinolf ;

Stachel, Daniel ;

Strahm, Brigitte ;

Woessmann, Wilhelm ;

Escherich, Gabriele ;

Zimmermann, Martin ;

Schrappe, Martin ;

Borkhardt, Arndt ;

Eckert, Cornelia ;

Bader, Peter ;

Uhrberg, Markus ;

Meisel, Roland .

BONE MARROW TRANSPLANTATION, 2019, 54 (11) :1847-1858

[3] Effect of Donor KIR2DL1 Allelic Polymorphism on the Outcome of Pediatric Allogeneic Hematopoietic Stem-Cell Transplantation [J].

Bari, Rafijul ;

Rujkijyanont, Piya ;

Sullivan, Erin ;

Kang, Guolian ;

Turner, Victoria ;

Gan, Kwan ;

Leung, Wing .

JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (30) :3782-+

[4] Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine245 [J].

Bari, Rafijul ;

Bell, Teresa ;

Leung, Wai-Hang ;

Vong, Queenie P. ;

Chan, Wing Keung ;

Das Gupta, Neha ;

Holladay, Martha ;

Rooney, Barbara ;

Leung, Wing .

BLOOD, 2009, 114 (25) :5182-5190

[5] Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell-mediated control of HIV-1, HCV, and HTLV-1 [J].

Boelen, Lies ;

Debebe, Bisrat ;

Silveira, Marcos ;

Salam, Arafa ;

MaKinde, Julia ;

Roberts, Chrissy H. ;

Wang, Eddie C. Y. ;

Frater, John ;

Gilmour, Jill ;

Twigger, Katie ;

Ladell, Kristin ;

Miners, Kelly L. ;

Jayaraman, Jyothi ;

Traherne, James A. ;

Price, David A. ;

Qi, Ying ;

Martin, Maureen P. ;

Macallan, Derek C. ;

Thio, Chloe L. ;

Astemborski, Jacquie ;

Kirk, Gregory ;

Donfield, Sharyne M. ;

Buchbinder, Susan ;

Khakoo, Salim, I ;

Goedert, James J. ;

Trowsdale, John ;

Carrington, Mary ;

Kollnberger, Simon ;

Asquith, Becca .

SCIENCE IMMUNOLOGY, 2018, 3 (29)

[6] Genetic epistasis between killer immunoglobulin-like receptors and human leukocyte antigens in Kawasaki disease susceptibility [J].

Bossi, G. ;

Mannarino, S. ;

Pietrogrande, M. C. ;

Salice, P. ;

Dellepiane, R. M. ;

Cremaschi, A. L. ;

Corana, G. ;

Tozzo, A. ;

Capittini, C. ;

De Silvestri, A. ;

Tinelli, C. ;

Pasi, A. ;

Martinetti, M. .

GENES AND IMMUNITY, 2015, 16 (07) :481-487

[7] Cellular ligands of activating NK receptors [J].

Bottino, C ;

Castriconi, R ;

Moretta, L ;

Moretta, A .

TRENDS IN IMMUNOLOGY, 2005, 26 (04) :221-226

[8] Natural killer cell education in human health and disease [J].

Boudreau, Jeanette E. ;

Hsu, Katharine C. .

CURRENT OPINION IN IMMUNOLOGY, 2018, 50 :102-111

[9] KIR3DL1/HLA-B Subtypes Govern Acute Myelogenous Leukemia Relapse After Hematopoietic Cell Transplantation [J].

Boudreau, Jeanette E. ;

Giglio, Fabio ;

Gooley, Ted A. ;

Stevenson, Philip A. ;

Le Luduec, Jean-Benoit ;

Shaffer, Brian C. ;

Rajalingam, Raja ;

Hou, Lihua ;

Hurley, Carolyn Katovich ;

Noreen, Harriet ;

Reed, Elaine F. ;

Yu, Neng ;

Vierra-Green, Cynthia ;

Haagenson, Michael ;

Malkki, Mari ;

Petersdorf, Effie W. ;

Spellman, Stephen ;

Hsu, Katharine C. .

JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (20) :2268-+

[10] Human and Rhesus Macaque KIR Haplotypes Defined by Their Transcriptomes [J].

Bruijnesteijn, Jesse ;

van der Wiel, Marit K. H. ;

Swelsen, Wendy T. N. ;

Otting, Nel ;

de Vos-Rouweler, Annemiek J. M. ;

Elferink, Dienne ;

Doxiadis, Gaby G. ;

Claas, Frans H. J. ;

Lardy, Neubury M. ;

de Groot, Natasja G. ;

Bontrop, Ronald E. .

JOURNAL OF IMMUNOLOGY, 2018, 200 (05) :1692-1701

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