Sentinel Lymph Node Biopsy in Cutaneous Squamous Cell Carcinoma Series of 37 Cases and Systematic Review of the Literature

被引：21

作者：

Lhote, Raphael ^{[1
]}

Lambert, Jerome ^{[2
]}

Lejeune, Julie ^{[2
]}

Gottlieb, Jeremy ^{[1
]}

Badaoui, Antoine ^{[3
]}

Battistella, Maxime ^{[3
,8
]}

Roux, Jennifer ^{[1
]}

Pages, Cecile ^{[1
]}

Vercellino, Laetitia ^{[4
]}

Vilmer, Catherine ^{[1
]}

Le Maignan, Christine ^{[5
]}

Escande, Catherine ^{[6
]}

Mbarek, Besma ^{[7
]}

Bagot, Martine ^{[1
,8
]}

Lebbe, Celeste ^{[1
,8
]}

Basset-Seguin, Nicole ^{[1
,8
]}

机构：

[1] St Louis Hosp, Dermatol Dept, Paris, France

[2] St Louis Hosp, SBIM, Paris, France

[3] St Louis Hosp, Pathol Dept, Paris, France

[4] St Louis Hosp, Dept Nucl Med, Paris, France

[5] St Louis Hosp, Oncol Dept, Paris, France

[6] St Louis Hosp, Oral & Maxillofacial Surg Dept, Paris, France

[7] St Louis Hosp, Dept Radiotherapy, Paris, France

[8] Paris 7 Diderot Univ, Paris, France

来源：

ACTA DERMATO-VENEREOLOGICA | 2018年 / 98卷 / 07期

关键词：

squamous cell carcinoma; sentinel lymph node; overall survival; relapse-free survival; ELECTIVE NECK DISSECTION; RISK-FACTORS; INTERDISCIPLINARY GUIDELINE; PROGNOSTIC FACTORS; SKIN; METASTASIS; METAANALYSIS; RECURRENCE; DIAGNOSIS; MELANOMA;

D O I：

10.2340/00015555-2942

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Cutaneous squamous cell carcinoma (cSSC) is one of the most common skin cancers and can lead to patient death. Early detection of node metastasis is a major goal for dermatologists and oncologists. The procedure sentinel lymph node biopsy has been proposed to improve early detection of node metastasis. The aim of this study was to evaluate the efficacy and impact of this technique on the prognosis of cSSC. A total of 37 patients (Saint Louis Hospital, Paris, France) who had undergone sentinel lymph node biopsy and 290 cases from the literature were analysed. The mean rate of positive sentinel lymph node biopsy was 0.14 [95% CI 0.09-0.22]. However, relapse-free survival and overall survival were not affected by sentinel lymph node status (log-rank test; p = 0.08 and p = 0.31, respectively), suggesting that this procedure is not mandatory in the management of cSSC.

引用

页码：671 / 676

页数：6

共 35 条

[1] Utility of sentinel node biopsy in patients with high-risk cutaneous squamous cell carcinoma [J].