The first chemical synthesis of wortmannin by starting from hydrocortisone

被引：36
|
作者：
Sato, S [1 ]
Nakada, M [1 ]
Shibasaki, M [1 ]
机构：
[1] UNIV TOKYO,FAC PHARMACEUT SCI,BUNKYO KU,TOKYO 113,JAPAN
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 34期
关键词：
D O I：
10.1016/0040-4039(96)01332-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first chemical synthesis of wortmannin, a potent and specific inhibitor of PI 3-kinases, was achieved by starting from commercially available and optically pure hydrocortisone. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码：6141 / 6144
页数：4
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