High incidence and mortality of pneumothorax in critically Ill patients with COVID-19

被引:55
作者
Wang, Xiao-hui [1 ]
Duan, Jun [1 ]
Han, Xiaoli [1 ]
Liu, Xinzhu [1 ]
Zhou, Junhao [3 ]
Wang, Xue [1 ]
Zhu, Linxiao [1 ]
Mou, Huaming [2 ]
Guo, Shuliang [1 ]
机构
[1] Chongqing Med Univ, Affiliated Hosp 1, Dept Resp & Crit Care Med, 1 Youyi Rd, Chongqing 400016, Peoples R China
[2] Chongqing Three Gorges Cent Hosp, Dept Cardiol, 165 Xincheng Rd, Chongqing 404000, Peoples R China
[3] Chongqing Three Gorges Cent Hosp, Dept Resp & Crit Care Med, Chongqing, Peoples R China
来源
HEART & LUNG | 2021年 / 50卷 / 01期
关键词
COVID-19; Pneumothorax; Epidemiology; Mortality; Mechanism; Prevention; Coronavirus disease 2019(COVID-19); RESPIRATORY-DISTRESS-SYNDROME; ACUTE LUNG INJURY;
D O I
10.1016/j.hrtlng.2020.10.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: The clinical characteristics of the patients with COVID-19 complicated by pneumothorax have not been clarified. Objectives: To determine the epidemiology and risks of pneumothorax in the critically ill patients with COVID-19. Methods: Retrospectively collecting and analysing medical records, laboratory findings, chest X-ray and CT images of 5 patients complicated by pneumothorax. Results: The incidence of pneumothorax was 10% (5/49) in patients with ARDS, 24% (5/21) in patients receiving mechanical ventilation, and 56% (5/9) in patients requiring invasive mechanical ventilation, with 80% (4/ 5) patients died. All the 5 patients were male and aged ranging from 54 to 79 years old. Pneumothorax was most likely to occur 2 weeks after the beginning of dyspnea and associated with reduction of neuromuscular blockers, recruitment maneuver, severe cough, changes of lung structure and function. Conclusions: Pneumothorax is a frequent and fatal complication of critically ill patients with COVID-19. (C) 2020 Published by Elsevier Inc.
引用
收藏
页码:37 / 43
页数:7
相关论文
共 28 条
[1]   Higher vs Lower Positive End-Expiratory Pressure in Patients With Acute Lung Injury and Acute Respiratory Distress Syndrome Systematic Review and Meta-analysis [J].
Briel, Matthias ;
Meade, Maureen ;
Mercat, Alain ;
Brower, Roy G. ;
Talmor, Daniel ;
Walter, Stephen D. ;
Slutsky, Arthur S. ;
Pullenayegum, Eleanor ;
Zhou, Qi ;
Cook, Deborah ;
Brochard, Laurent ;
Richard, Jean-Christophe M. ;
Lamontagne, Francois ;
Bhatnagar, Neera ;
Stewart, Thomas E. ;
Guyatt, Gordon .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 303 (09) :865-873
[2]   Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. [J].
Brower, RG ;
Matthay, MA ;
Morris, A ;
Schoenfeld, D ;
Thompson, BT ;
Wheeler, A ;
Wiedemann, HP ;
Arroliga, AC ;
Fisher, CJ ;
Komara, JJ ;
Perez-Trepichio, P ;
Parsons, PE ;
Wolkin, R ;
Welsh, C ;
Fulkerson, WJ ;
MacIntyre, N ;
Mallatratt, L ;
Sebastian, M ;
McConnell, R ;
Wilcox, C ;
Govert, J ;
Thompson, D ;
Clemmer, T ;
Davis, R ;
Orme, J ;
Weaver, L ;
Grissom, C ;
Eskelson, M ;
Young, M ;
Gooder, V ;
McBride, K ;
Lawton, C ;
d'Hulst, J ;
Peerless, JR ;
Smith, C ;
Brownlee, J ;
Pluss, W ;
Kallet, R ;
Luce, JM ;
Gottlieb, J ;
Elmer, M ;
Girod, A ;
Park, P ;
Daniel, B ;
Gropper, M ;
Abraham, E ;
Piedalue, F ;
Glodowski, J ;
Lockrem, J ;
McIntyre, R .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (18) :1301-1308
[3]   Lung protective ventilation Currently underused-to the detriment of patients [J].
Camporota, Luigi ;
Hart, Nicholas .
BRITISH MEDICAL JOURNAL, 2012, 344
[4]   Feasibility and safety of extracorporeal CO2 removal to enhance protective ventilation in acute respiratory distress syndrome: the SUPERNOVA study [J].
Combes, Alain ;
Fanelli, Vito ;
Pham, Tai ;
Ranieri, V. Marco ;
Goligher, Ewan C. ;
Brodie, Daniel ;
Pesenti, Antonio ;
Beale, Richard ;
Brochard, Laurent ;
Chiche, Jean-Daniel ;
Fan, Eddy ;
de Backer, Daniel ;
Francois, Guy ;
Ferguson, Niall ;
Laffey, John ;
Mercat, Alain ;
McAuley, Daniel F. ;
Mueller, Thomas ;
Quintel, Michael ;
Vincent, Jean-Louis ;
Taccone, Fabio Silvio ;
Peperstraete, Harlinde ;
Morimont, Philippe ;
Schmidt, Matthieu ;
Levy, Bruno ;
Diehl, Jean-Luc ;
Guervilly, Christophe ;
Capelier, Gilles ;
Vieillard-Baron, Antoine ;
Messika, Jonathan ;
Karagiannidis, Christian ;
Moerer, Onnen ;
Urbino, Rosario ;
Antonelli, Massimo ;
Mojoli, Francesco ;
Alessandri, Francesco ;
Grasselli, Giacomo ;
Donker, Dirk ;
Ferrer, Ricard ;
Mancebo, Jordi ;
Slutsky, Arthur S. .
INTENSIVE CARE MEDICINE, 2019, 45 (05) :592-600
[5]   Alveolar overdistension is an important mechanism of persistent lung damage following severe protracted ARDS [J].
Finfer, S ;
Rocker, G .
ANAESTHESIA AND INTENSIVE CARE, 1996, 24 (05) :569-573
[6]  
Gao Z W, 2019, Zhonghua Yi Xue Za Zhi, V99, P3819, DOI 10.3760/cma.j.issn.0376-2491.2019.48.012
[7]   LUNG STRUCTURE AND FUNCTION IN DIFFERENT STAGES OF SEVERE ADULT-RESPIRATORY-DISTRESS-SYNDROME [J].
GATTINONI, L ;
BOMBINO, M ;
PELOSI, P ;
LISSONI, A ;
PESENTI, A ;
FUMAGALLI, R ;
TAGLIABUE, M .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 271 (22) :1772-1779
[8]  
Ghiani Alessandro, 2018, Case Rep Crit Care, V2018, P9736217, DOI 10.1155/2018/9736217
[9]   FIFTY YEARS OF RESEARCH IN ARDS Respiratory Mechanics in Acute Respiratory Distress Syndrome [J].
Henderson, William R. ;
Chen, Lu ;
Amato, Marcelo B. P. ;
Brochard, Laurent J. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 196 (07) :822-833
[10]   EXTRACORPOREAL GAS-EXCHANGE IN ADULT RESPIRATORY-DISTRESS SYNDROME - ASSOCIATED MORBIDITY AND ITS SURGICAL-TREATMENT [J].
WAGNER, PK ;
KNOCH, M ;
SANGMEISTER, C ;
MULLER, E ;
LENNARTZ, H ;
ROTHMUND, M .
BRITISH JOURNAL OF SURGERY, 1990, 77 (12) :1395-1398