Genetic susceptibility of mice to Candida albicans vaginitis correlates with host estrogen sensitivity

被引：31
作者：
Clemons, KV
Spearow, JL
Parmar, R
Espiritu, M
Stevens, DA
机构：
[1] Santa Clara Valley Med Ctr, Div Infect Dis, Dept Med, San Jose, CA 95128 USA
[2] Calif Inst Med Res, San Jose, CA 95128 USA
[3] Stanford Univ, Dept Med, Div Dis & Geog Med, Stanford, CA 94305 USA
[4] Univ Calif Davis, Sect Neurobiol Physiol & Behav, Davis, CA 95616 USA
来源：
INFECTION AND IMMUNITY | 2004年 / 72卷 / 08期
关键词：
D O I：
10.1128/IAI.72.8.4878-4880.2004
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We compared susceptibility to Candida vaginitis in derived murine substrains differing in sensitivity to estrogen (CD-1 and CD10, resistant; CD3 and C57BL/6 responsive), and in F1 crosses. The order of decreasing resistance was CD-1 greater than or equal to CD10 greater than or equal to CD10 x CD3F1 > CD10 x B6F1 > CD3 > C57BL/6 and correlated with estrogen responsiveness in endocrine disruptor assays. Resistance to Candida vaginitis appears additive in CD10 x B6F1 animals and dominant in CD10 x CD3F1 animals.
引用
收藏
页码：4878 / 4880
页数：3
相关论文
共 21 条
  • [1] Prevalence of vulvovaginal candidiasis and susceptibility to fluconazole in women
    Bauters, TGM
    Dhont, MA
    Temmerman, MIL
    Nelis, HJ
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2002, 187 (03) : 569 - 574
  • [2] MATURITY AS A CRITICAL DETERMINANT OF RESISTANCE TO FUNGAL-INFECTIONS - STUDIES IN MURINE BLASTOMYCOSIS
    BRASS, C
    STEVENS, DA
    [J]. INFECTION AND IMMUNITY, 1982, 36 (01) : 387 - 395
  • [3] BRUMMER E, 1984, Journal of Experimental Pathology (New York), V1, P241
  • [4] Calderon L, 2003, MED MYCOL, V41, P143, DOI 10.1080/mmy.41.2.143.147
  • [5] EXAMINATION OF EFFECT OF AGE AND ACQUIRED-IMMUNITY ON SUSCEPTIBILITY OF MICE TO INFECTION WITH ASPERGILLUS-FUMIGATUS
    CORBEL, MJ
    EADES, SM
    [J]. MYCOPATHOLOGIA, 1977, 60 (02) : 79 - 85
  • [6] Oestrogen, glycogen and vaginal candidiasis
    Dennerstein, GJ
    Ellis, DH
    [J]. AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, 2001, 41 (03) : 326 - 328
  • [7] Effects of reproductive hormones on experimental vaginal candidiasis
    Fidel, PL
    Cutright, J
    Steele, C
    [J]. INFECTION AND IMMUNITY, 2000, 68 (02) : 651 - 657
  • [8] LOOSE DS, 1983, J GEN MICROBIOL, V129, P2379
  • [9] CANDIDA-ALBICANS ESTROGEN-BINDING PROTEIN GENE ENCODES AN OXIDOREDUCTASE THAT IS INHIBITED BY ESTRADIOL
    MADANI, ND
    MALLOY, PJ
    RODRIGUEZPOMBO, P
    KRISHNAN, AV
    FELDMAN, D
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (03) : 922 - 926
  • [10] O'Connor C, 1998, Infect Dis Obstet Gynecol, V6, P176, DOI 10.1002/(SICI)1098-0997(1998)6:4<176::AID-IDOG7>3.0.CO
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