3-(3-Chloroanilino)-1-(3,5-dimethyl-1H-pyrazol-1-yl)propan-1-one

被引:2
作者
Saeed, Aamer [2 ]
Hussain, Shahid [2 ]
Bolte, Michael [1 ]
机构
[1] Goethe Univ Frankfurt, Inst Anorgan Chem, D-60438 Frankfurt, Germany
[2] Quaid I Azam Univ, Dept Chem, Islamabad, Pakistan
来源
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2009年 / 65卷
关键词
D O I
10.1107/S1600536809016250
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
In the molecule of the title compound, C14H16ClN3O, the benzene and pyrazole rings are oriented at a dihedral angle of 3.50 (3)degrees. In the crystal structure, intermolecular N-H center dot center dot center dot O hydrogen bonds link the molecules into chains. A pi-pi contact between the benzene and pyrazole rings [centroid-centroid distance = 3.820 (3) angstrom] may further stabilize the structure.
引用
收藏
页码:O1231 / U1413
页数:10
相关论文
共 13 条
  • [1] Gastrointestinal effects of selective and non-selective non-steroidal anti-inflammatory drugs
    Akarca, US
    [J]. CURRENT PHARMACEUTICAL DESIGN, 2005, 11 (14) : 1779 - 1793
  • [2] TABLES OF BOND LENGTHS DETERMINED BY X-RAY AND NEUTRON-DIFFRACTION .1. BOND LENGTHS IN ORGANIC-COMPOUNDS
    ALLEN, FH
    KENNARD, O
    WATSON, DG
    BRAMMER, L
    ORPEN, AG
    TAYLOR, R
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1987, (12): : S1 - S19
  • [3] AN EMPIRICAL CORRECTION FOR ABSORPTION ANISOTROPY
    BLESSING, RH
    [J]. ACTA CRYSTALLOGRAPHICA SECTION A, 1995, 51 : 33 - 38
  • [4] BLESSING RH, 1995, ACTA CRYSTALLOGR A, V51, P38
  • [5] Elguero J., 2002, Pyrazoles as Drugs: Facts and Fantasies, Targets in Heterocyclic Systems, V6, P52, DOI DOI 10.12691/WJOC-5-1-4
  • [6] Oral anticoagulants in development - Focus on thromboprophylaxis in patients undergoing orthopaedic surgery
    Eriksson, Bengt I.
    Quinlan, Daniel J.
    [J]. DRUGS, 2006, 66 (11) : 1411 - 1429
  • [7] Rivaroxaban.: Factor Xa inhibitor, anticoagulant.
    Escolar, G.
    Villalta, J.
    Casals, F.
    Bozzo, J.
    Serradell, N.
    Bolos, J.
    [J]. DRUGS OF THE FUTURE, 2006, 31 (06) : 484 - 493
  • [8] On the photochemical behaviour of some diarylpyrazolines
    Mella, M
    Fagnoni, M
    Viscardi, G
    Savarino, P
    Elisei, F
    Albini, A
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 1997, 108 (2-3) : 143 - 148
  • [9] Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)
    Penning, TD
    Talley, JJ
    Bertenshaw, SR
    Carter, JS
    Collins, PW
    Docter, S
    Graneto, MJ
    Lee, LF
    Malecha, JW
    Miyashiro, JM
    Rogers, RS
    Rogier, DJ
    Yu, SS
    Anderson, GD
    Burton, EG
    Cogburn, JN
    Gregory, SA
    Koboldt, CM
    Perkins, WE
    Seibert, K
    Veenhuizen, AW
    Zhang, YY
    Isakson, PC
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (09) : 1347 - 1365
  • [10] Microwave-accelerated synthesis of some 1-aroyl-3,5-dimethylpyrazoles
    Saeed, Aamer
    Mumtaz, Amara
    [J]. CHINESE CHEMICAL LETTERS, 2008, 19 (11) : 1305 - 1308