Case of a Two-Year-Old Boy With Recurrent Seizures, Abnormal Movements, and Central Hypoventilation

被引:3
作者
Cohen, Alexander L. [1 ]
Wong-Kisiel, Lily C. [1 ]
机构
[1] Mayo Clin, Coll Med, Div Child & Adolescent Neurol, Dept Neurol, Rochester, MN 55905 USA
关键词
NMDA-RECEPTOR ENCEPHALITIS; STATUS EPILEPTICUS; OVARIAN TERATOMA; DISORDER; CHILDREN;
D O I
10.1016/j.spen.2014.04.014
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis was first described in young women with ovarian teratoma. Typical presentations include subacute onset of neuropsychiatric symptoms, seizures, altered awareness, movement disorders, and autonomic dysfunction. Growing evidence indicates that anti-NMDAR encephalitis is one of the most common causes of encephalitis in children and young adults. We present a case of a 2 year-old boy with anti-NMDAR encephalitis to illustrate and discuss the differences in neurological presentation, frequency of symptoms, and association with underlying tumor between children and adults. (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:114 / 118
页数:5
相关论文
共 18 条
[1]   Autoimmune Encephalitis in Children [J].
Armangue, Thais ;
Petit-Pedrol, Mar ;
Dalmau, Josep .
JOURNAL OF CHILD NEUROLOGY, 2012, 27 (11) :1460-1469
[2]   Complex partial status epilepticus revealing anti-NMDA receptor encephalitis [J].
Bayreuther, Caroline ;
Bourg, Veronique ;
Dellamonica, Jean ;
Borg, Michel ;
Bernardin, Gilles ;
Thomas, Pierre .
EPILEPTIC DISORDERS, 2009, 11 (03) :261-265
[3]   Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma [J].
Dalmau, Josep ;
Tuzun, Erdem ;
Wu, Hai-yan ;
Masjuan, Jaime ;
Rossi, Jeffrey E. ;
Voloschin, Alfredo ;
Baehring, Joachim M. ;
Shimazaki, Haruo ;
Koide, Rej ;
King, Dale ;
Mason, Warren ;
Sansing, Lauren H. ;
Dichter, Marc A. ;
Rosenfeld, Myrna R. ;
Lynch, David R. .
ANNALS OF NEUROLOGY, 2007, 61 (01) :25-36
[4]   Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis [J].
Dalmau, Josep ;
Lancaster, Eric ;
Martinez-Hernandez, Eugenia ;
Rosenfeld, Myrna R. ;
Balice-Gordon, Rita .
LANCET NEUROLOGY, 2011, 10 (01) :63-74
[5]   Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies [J].
Dalmau, Josep ;
Gleichman, Amy J. ;
Hughes, Ethen G. ;
Rossi, Jeffrey E. ;
Peng, Xiaoyu ;
Lai, Meizan ;
Dessain, Scott K. ;
Rosenfeld, Mynna R. ;
Balice-Gordon, Rita ;
Lynch, David R. .
LANCET NEUROLOGY, 2008, 7 (12) :1091-1098
[6]   Anti-NMDA-Receptor Encephalitis: Case Report and Literature Review of an Under-Recognized Condition [J].
Day, Gregory S. ;
High, Sasha M. ;
Cot, Bianca ;
Tang-Wai, David F. .
JOURNAL OF GENERAL INTERNAL MEDICINE, 2011, 26 (07) :811-816
[7]   Anti-N-Methyl-D-Aspartate Receptor (NMDAR) Encephalitis in Children and Adolescents [J].
Florance, Nicole R. ;
Davis, Rebecca L. ;
Lam, Christopher ;
Szperka, Christina ;
Zhou, Lei ;
Ahmad, Saba ;
Campen, Cynthia J. ;
Moss, Heather ;
Peter, Nadja ;
Gleichman, Amy J. ;
Glaser, Carol A. ;
Lynch, David R. ;
Rosenfeld, Myrna R. ;
Dalmau, Josep .
ANNALS OF NEUROLOGY, 2009, 66 (01) :11-18
[8]   Anti-NMDA receptor encephalitis: report of ten cases and comparison with viral encephalitis [J].
Gable, M. S. ;
Gavali, S. ;
Radner, A. ;
Tilley, D. H. ;
Lee, B. ;
Dyner, L. ;
Collins, A. ;
Dengel, A. ;
Dalmau, J. ;
Glaser, C. A. .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2009, 28 (12) :1421-1429
[9]   Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study [J].
Granerod, Julia ;
Ambrose, Helen E. ;
Davies, Nicholas W. S. ;
Clewley, Jonathan P. ;
Walsh, Amanda L. ;
Morgan, Dilys ;
Cunningham, Richard ;
Zuckerman, Mark ;
Mutton, Ken J. ;
Solomon, Tom ;
Ward, Katherine N. ;
Lunn, Michael P. T. ;
Irani, Sarosh R. ;
Vincent, Angela ;
Brown, David W. G. ;
Crowcroft, Natasha S. .
LANCET INFECTIOUS DISEASES, 2010, 10 (12) :835-844
[10]   Anti-NMDA receptor encephalitis presenting with imaging findings and clinical features mimicking Rasmussen syndrome [J].
Greiner, Hansel ;
Leach, James L. ;
Lee, Ki-Hyeong ;
Krueger, Darcy A. .
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2011, 20 (03) :266-270