Comparative analysis of the incidence of surgical site infections in patients with liver resection for colorectal hepatic metastases after neoadjuvant chemotherapy

被引：21
作者：
Scilletta, Roberto [1 ]
Pagano, Duilio [2 ]
Spada, Marco [2 ]
Mongiovi, Sebastiano [3 ]
Pesce, Antonio [1 ]
Portale, Teresa R. [1 ]
Guardabasso, Vincenzo [4 ]
Puleo, Stefano [1 ]
Gruttadauria, Salvatore [2 ]
机构：
[1] Univ Catania, Dept Surg Sci, Azienda Osped Univ Policlin Vittorio Emanuele, I-95100 Catania, Italy
[2] Univ Pittsburgh, Med Ctr Italy, Dept Surg, Mediterranean Inst Transplantat & Adv Specialized, Palermo, Italy
[3] Humanitas Ctr Catanese Oncol, Dept Abdominal Oncol Surg, Catania, Italy
[4] Azienda Osped Univ Policlin Vittorio Emanuele, Catania, Italy
来源：
JOURNAL OF SURGICAL RESEARCH | 2014年 / 188卷 / 01期
关键词：
Colorectal liver metastases; Surgical site infection; Clavien-Dindo classification; Neoadjuvant chemotherapy; Liver surgery; Risk factors; QUALITY IMPROVEMENT PROGRAM; CANCER; COMPLICATIONS; SURGERY; BEVACIZUMAB; PREVENTION; INJURY; RATES;
D O I：
10.1016/j.jss.2013.11.1092
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Background: The aim of this study was to identify the incidence of surgical site infections (SSIs) and postoperative complications, as defined by the Clavien-Dindo classification, after hepatic resection for metastatic colorectal cancer in patients with and without associated neoadjuvant chemotherapy. Methods: A total of 181 patients were studied retrospectively. Patients were divided into two groups: the first group comprised patients with associated neoadjuvant chemotherapeutic treatment for liver metastases with a latency time < 8 wk and the second group comprised patients without associated neoadjuvant chemotherapy. Results: Variables of duration of liver surgery, length of total hospital stay, and length of postoperative hospital stay seem to be correlated with SSIs and postoperative complications, P < 0.005 and P < 0.0001, respectively. Duration of surgery is a risk factor for SSIs, with an odds ratio of 1.15, and for complications according to the Clavien-Dindo classification, with an odds ratio of 1.35. Conclusions: Neoadjuvant chemotherapy was not a significant risk factor for SSIs, whereas the total length of hospital stay, length of postoperative hospital stay, and duration of surgery were independent predictors of SSIs and complications according to the Clavien-Dindo classification. (C) 2014 Elsevier Inc. All rights reserved.
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收藏
页码：183 / 189
页数：7
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