Mechanisms of upper limb amyotrophy in spinal disorders

被引:15
作者
Foster, Emma [1 ]
Tsang, Benjamin K. -T. [1 ]
Kam, Anthony [2 ,3 ]
Stark, Richard J. [1 ,4 ]
机构
[1] Alfred Hlth, Dept Neurosci, Melbourne, Vic, Australia
[2] Alfred Hlth, Dept Radiol, Melbourne, Vic, Australia
[3] Monash Univ, Melbourne, Vic 3004, Australia
[4] Monash Univ, Dept Med, Melbourne, Vic 3800, Australia
关键词
Cervical spinal cord; High cord compression; Hirayama disease; Spinal cyst; JUVENILE MUSCULAR-ATROPHY; CLINICAL-FEATURES; CORD; COMPRESSION; HAND;
D O I
10.1016/j.jocn.2013.10.035
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Upper limb amyotrophy may occur as an indirect consequence of various spinal disorders, including ventral longitudinal intraspinal fluid collection, Hirayama disease and high cervical cord compression. We present patients who suffer from each of these and review the literature on the three conditions with emphasis on the pathogenesis of amyotrophy. We propose that pathology some distance from the lower cervical spinal cord may affect normal venous drainage, resulting in venous congestion and reduced perfusion pressure which, in turn, could result in anterior horn cell dysfunction in all three disorders. (c) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1209 / 1214
页数:6
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