A nonhealing ulcer diagnosed as extramedullary plasmocytoma of the limb eight years after cardiac transplantation

被引:13
作者
Ibe, W [1 ]
Wittlinger, T [1 ]
Sebastian, P [1 ]
Meyer, J [1 ]
Darius, H [1 ]
机构
[1] Univ Mainz, Dept Med 2, D-55101 Mainz, Germany
关键词
D O I
10.1097/00007890-199909270-00025
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A 63-year-old man was hospitalized for a nonhealing ulcer of the left lower leg that appeared 8 years after orthotopic cardiac transplantation under immunosuppressive therapy including cyclosporine. Serum protein electrophoresis, immunofixation, and urinalysis revealed a monoclonal gammopathy IgG kappa, The final diagnosis of an extramedullary plasmocytoma was made by biopsy of the ulcer, which showed formations of plasmablastic cells. We report a rare case of extramedullary plasmocytoma as a posttransplantational malignancy.
引用
收藏
页码:901 / 904
页数:4
相关论文
共 16 条
[1]   CYCLOSPORIN-A PROMOTES SPONTANEOUS OUTGROWTH INVITRO OF EPSTEIN-BARR VIRUS-INDUCED B-CELL LINES [J].
BIRD, AG ;
MCLACHLAN, SM ;
BRITTON, S .
NATURE, 1981, 289 (5795) :300-301
[2]   THE RISK OF NEOPLASMS IN PATIENTS TREATED WITH CYCLOSPORINE-A [J].
COCKBURN, ITR ;
KRUPP, P .
JOURNAL OF AUTOIMMUNITY, 1989, 2 (05) :723-731
[3]  
JENSEN MK, 1967, ACTA MED SCAND, V182, P445
[4]  
KNOWLING MA, 1983, CLIN ONCOL, V37, P255
[5]  
PENN I, 1991, TRANSPLANT P, V23, P1101
[6]  
PENN I, 1992, CLIN TRANSPLANT, V6, P275
[7]  
PENN I, 1987, TRANSPLANTATION, V43, P2211
[8]  
SAMSON D, 1989, LANCET, V2, P882
[9]   MULTIPLE EXTRAMEDULLARY PLASMACYTOMAS FOLLOWING ORTHOTOPIC LIVER-TRANSPLANTATION IN A PATIENT ON CYCLOSPORINE THERAPY [J].
SCHEMANKEWITZ, E ;
HAMMAMI, A ;
STAHL, R ;
HENDERSON, JM ;
CHECK, IJ .
TRANSPLANTATION, 1990, 49 (05) :1019-1022
[10]  
SHEIL AGR, 1991, CLIN TRANSPLANT, V5, P573