Antitubercular Lanostane Triterpenes from Cultures of the Basidiomycete Ganoderma sp BCC 16642

被引：30

作者：

Isaka, Masahiko ^{[1
]}

Chinthanom, Panida ^{[1
]}

Sappan, Malipan ^{[1
]}

Danwisetkanjana, Kannawat ^{[1
]}

Boonpratuang, Thitiya ^{[1
]}

Choeyklin, Rattaket ^{[2
]}

机构：

[1] Natl Ctr Genet Engn & Biotechnol BIOTEC, 113 Thailand Sci Pk,Phaholyothin Rd, Klongluang 12120, Pathumthani, Thailand

[2] Biodivers Based Econ Dev Off, Govt Complex,Chaeng Wattana Rd, Bangkok 10210, Thailand

来源：

JOURNAL OF NATURAL PRODUCTS | 2016年 / 79卷 / 01期

关键词：

ACID; METABOLITES; MYCELIA;

D O I：

10.1021/acs.jnatprod.5b00826

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Sixteen new lanostane triterpenoids (1-16), together with 26 known compounds (17-42), were isolated from cultures of the basidiomycete Ganoderma sp. BCC 16642. Antitubercular activities of these Ganoderma lanostanoids against Mycobacterium tuberculosis H37Ra were evaluated, and structure-activity relationships are proposed.

引用

页码：161 / 169

页数：9

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