Visit-to-visit blood pressure variability and dementia

被引：27
作者：
Nagai, Michiaki [1 ]
Hoshide, Satoshi [2 ]
Dote, Keigo [1 ]
Kario, Kazuomi [2 ]
机构：
[1] Hiroshima City Asa Hosp, Dept Cardiol, Hiroshima, Japan
[2] Jichi Med Univ, Sch Med, Dept Med, Div Cardiovasc Med, Shimotsuke, Tochigi 3290498, Japan
来源：
GERIATRICS & GERONTOLOGY INTERNATIONAL | 2015年 / 15卷
关键词：
Alzheimer's disease; cognitive impairment; Hypertension; stroke; visit-to-visit blood pressure variability; ALZHEIMERS-DISEASE; COGNITIVE FUNCTION; INDEPENDENT DETERMINANTS; ELDERLY ASSOCIATIONS; AMYLOID DEPOSITION; BRAIN INFARCTION; MOUSE MODEL; HEART-RATE; HIGH-RISK; ATHEROSCLEROSIS;
D O I：
10.1111/ggi.12660
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Visit-to-visit blood pressure variability has been shown to be an independent risk factor for stroke and cognitive impairment. However, the underlying mechanisms are not fully understood. Artery remodeling and silent cerebral injury are suggested to be involved in the relationship between visit-to-visit blood pressure variability and cognitive impairment. The present review article summarizes the recent literature on these topics. Here we review visit-to-visit blood pressure variability, artery remodeling, silent cerebral injury and an issue regarding the impact of these components on dementia including Alzheimer's disease. Geriatr Gerontol Int 2015; 15 (Suppl. 1): 26-33.
引用
收藏
页码：26 / 33
页数：8
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