Multi-level collagen aggregates and their applications in biomedical applications

被引：17

作者：

Dan, Weihua ^{[1
,2
]}

Chen, Yining ^{[1
,2
]}

Dan, Nianhua ^{[1
,2
]}

Zheng, Xin ^{[1
,2
]}

Wang, Lu ^{[1
,2
]}

Yang, Changkai ^{[1
,2
]}

Huang, Yanping ^{[1
,2
]}

Liu, Xinhua ^{[1
,3
]}

Hu, Yang ^{[1
,4
]}

机构：

[1] Sichuan Univ, Minist Educ, Key Lab Leather Chem & Engn, Chengdu 610065, Sichuan, Peoples R China

[2] Sichuan Univ, Natl Engn Lab Clean Technol Leather Manufacture, Chengdu, Sichuan, Peoples R China

[3] Shaanxi Univ Sci & Technol, Coll Bioresources Chem & Mat Engn, Xian, Shaanxi, Peoples R China

[4] Huazhong Agr Univ, Key Lab Environm Correlat Dietol, Minist Educ, Wuhan, Hubei, Peoples R China

来源：

INTERNATIONAL JOURNAL OF POLYMER ANALYSIS AND CHARACTERIZATION | 2019年 / 24卷 / 08期

基金：

中国国家自然科学基金;

关键词：

Collagen; collagen fibers; collagen aggregates; collagen modification and application; ACELLULAR DERMAL MATRIX; OXIDIZED CHITOSAN OLIGOSACCHARIDE; CROSS-LINKING; BREAST RECONSTRUCTION; ELECTROSPUN; DIALDEHYDE; BONE; FEASIBILITY; FILM;

D O I：

10.1080/1023666X.2019.1656387

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

In this review, the system of multi-level collagen aggregates including collagen molecular, collagen fiber, advanced collagen aggregates, and tissues was reviewed. The preparation methods of multi-level collagen aggregates were introduced, and the relationship between structure and properties of them was analyzed and clarified. The general rule of structure-activity relationship of multi-level collagen aggregates under different modifiers and modified conditions was analyzed, and a theoretical basis for the application of multi-level collagen aggregates in biomedical field was provided. Finally, the applications of a series of biomedical materials of multi-level collagen aggregates and their modified products were listed. It is confirmed that the application field of multi-level collagen aggregates and their modified products might be far greater than collagen and other biomass. The multi-level collagen aggregates might have a very broad application prospect.

引用

页码：667 / 683

页数：17

共 59 条

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