Effective Treatment of Adult Parasomnias with Keishikaryukotsuboreito in Four Cases

被引：1
作者：
Tamada, Mayumi [1 ,2 ]
Ueno, Shinji [1 ]
Watanabe, Kako [2 ]
Muramatsu, Shin-ichi [1 ,3 ]
机构：
[1] Jichi Med Univ, Div Oriental Med, Ctr Community Med, Tochigi, Japan
[2] Azabu Muse Clin, Tokyo, Japan
[3] Jichi Med Univ, Div Neurol, Dept Med, Tochigi, Japan
来源：
INTERNAL MEDICINE | 2022年 / 61卷 / 09期
关键词：
Key words; Keisikaryukotsuboreito; parasomnia; REM sleep behavior disorder; SLEEP BEHAVIOR DISORDER; PARKINSONS-DISEASE; MARKER;
D O I：
10.2169/internalmedicine.7952-21
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Parasomnias are undesirable behaviors or experiences during sleep that manifest clinically as abnormal behavior, emotions, and nightmares. We herein report four elderly parasomnia patients who were successfully treated for abnormal nocturnal behaviors, including rapid eye movement (REM) sleep behavior disorders, with Keishikaryukotsuboreito (KRB), a Japanese traditional herbal medicine. KRB resolved nocturnal violent behaviors and sleep walking without any adverse effects. In one patient, occipital dominant spike-wave complexes induced by 3-Hz photic stimulation were reduced after KRB treatment, suggesting that KRB has inhibitory effects on brain irritability. KRB may represent a safe therapeutic option for treating parasomnias in the elderly.
引用
收藏
页码：1433 / 1438
页数：6
相关论文
共 25 条
  • [1] REM sleep behavior disorder: Mimics and variants
    Antelmi, Elena
    Lippolis, Marianna
    Biscarini, Francesco
    Tinazzi, Michele
    Plazzi, Giuseppe
    [J]. SLEEP MEDICINE REVIEWS, 2021, 60
  • [2] Subregional 6-[18F]fluoro-L-m-tyrosine Uptake in the Striatum in Parkinson's Disease
    Asari, Sayaka
    Fujimoto, Ken-ichi
    Miyauchi, Akihiro
    Sato, Toshihiko
    Nakano, Imaharu
    Muramatsu, Shin-ichi
    [J]. BMC NEUROLOGY, 2011, 11
  • [3] Parasomnia overlap disorder, Parkinson's disease and subthalamic deep brain stimulation: three case reports
    Bargiotas, Panagiotis
    Muellner, Julia
    Schuepbach, W. M. Michael
    Bassetti, Claudio L.
    [J]. BMC NEUROLOGY, 2017, 17
  • [4] Rapid eye movement sleep behavior disorder and the link to alpha-synucleinopathies
    Barone, Daniel A.
    Henchcliffe, Claire
    [J]. CLINICAL NEUROPHYSIOLOGY, 2018, 129 (08) : 1551 - 1564
  • [5] Boeve BF, 2013, LANCET NEUROL, V12, P469, DOI 10.1016/S1474-4422(13)70054-1
  • [6] NREM sleep parasomnias as disorders of sleep-state dissociation
    Castelnovo, Anna
    Lopez, Regis
    Proserpio, Paola
    Nobili, Lino
    Dauvilliers, Yves
    [J]. NATURE REVIEWS NEUROLOGY, 2018, 14 (08) : 470 - 481
  • [7] Rapid-eye-movement sleep behaviour disorder and neurodegenerative diseases
    Gagnon, JF
    Postuma, RB
    Mazza, S
    Doyon, J
    Montplaisir, J
    [J]. LANCET NEUROLOGY, 2006, 5 (05) : 424 - 432
  • [8] Idiopathic REM sleep behaviour disorder and neurodegeneration - an update
    Hoegl, Birgit
    Stefani, Ambra
    Videnovic, Aleksandar
    [J]. NATURE REVIEWS NEUROLOGY, 2018, 14 (01) : 40 - 55
  • [9] Rapid-eye-movement sleep behaviour disorder as an early marker for a neurodegenerative disorder:: a descriptive study
    Iranzo, Alex
    Molinuevo, Jose Luis
    Santamaria, Joan
    Serradell, Monica
    Marti, Maria Jose
    Valldeoriola, Francesc
    Tolosa, Eduard
    [J]. LANCET NEUROLOGY, 2006, 5 (07) : 572 - 577
  • [10] Potential Application of Yokukansan as a Remedy for Parkinson's Disease
    Jang, Jung-Hee
    Jung, Kyungsook
    Kim, Joong-Sun
    Jung, Inchul
    Yoo, Horyong
    Moon, Changjong
    [J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, 2018
123