BINAP/1 4-diamine-ruthenium(II) complexes for efficient asymmetric hydrogenation of 1-tetralones and analogues

被引：97

作者：

Ohkuma, T ^{[1
]}

Hattori, T

Ooka, H

Inoue, T

Noyori, R

机构：

[1] Nagoya Univ, Dept Chem, Nagoya, Aichi 4648602, Japan

[2] Nagoya Univ, Res Ctr Mat Sci, Nagoya, Aichi 4648602, Japan

[3] Nippon Soda Co Ltd, Odawara Res Ctr, Odawara, Kanagawa 2500280, Japan

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 16期

关键词：

D O I：

10.1021/ol049157c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A combined system of a RuCl2(binap)(1,4-diamine) complex and t-C4H9OK in i-C3H7OH catalyzes enantioselective hydrogenation of various 1-tetralone derivatives and some methylated 2-cyclohexenones. Hydrogenation of 2-methyl-1-tetralone under dynamic kinetic resolution gives the cis alcohol with high ee.

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页码：2681 / 2683

页数：3

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