Orofacial Rhabdomyosarcoma: Report of a case and review of the literature

被引:0
作者
Gordon-Nunez, Manuel A. [1 ]
Piva, Marta R. [2 ]
Dos Anjos, Edvaldo D. [3 ]
Freitas, Roseana A. [4 ]
机构
[1] Panama UFRN, IFARHU SENACYT, Doctoral & Postdoctoral Scholarships Program 2005, Natal, RN, Brazil
[2] UFS, Discipline Oral Pathol, Aracaju S, Brazil
[3] Univ Tiradentes, Discipline Bucomaxillofacial Surg, Aracaju S, Brazil
[4] Univ Fed Rio Grande do Norte, UFRN, Post Grad Program Oral Pathol, BR-59072970 Natal, RN, Brazil
来源
MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL | 2008年 / 13卷 / 12期
关键词
Rhabdomyosarcoma; childhood; orofacial; immunohistochemistry;
D O I
暂无
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Rhabdomyosarcomas (RMS) are among the most common soft-tissue tumors in children. These tumors are derived from mesenchymal tissue with a tendency toward myogenic differentiation that probably originates from immature and highly invasive satellite cells associated with the embryogenesis of skeletal muscle. Some of these tumors are associated with high rates of recurrence and metastasis. The diagnosis is made by microscopic analysis and auxiliary techniques such as immunohistochemistry, electron microscopy, cytogenetic analysis, and molecular biology. We report here a case of orofacial RMS in a 4-year-old child and provide an updated review of the literature, focusing mainly on the clinicopathological aspects, diagnosis and treatment of RMS of the head and neck.
引用
收藏
页码:E765 / E769
页数:5
相关论文
共 17 条
[11]   Treatment of localized nonorbital, nonparameningeal head and neck rhabdomyosarcoma: Lessons learned from intergroup rhabdomyosarcoma studies III and IV [J].
Pappo, AS ;
Meza, JL ;
Donaldson, SS ;
Wharam, MD ;
Wiener, ES ;
Qualman, SJ ;
Maurer, HM ;
Crist, WM .
JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (04) :638-645
[12]   Pathologic classification of rhabdomyosarcomas and correlations with molecular studies [J].
Parham, DM .
MODERN PATHOLOGY, 2001, 14 (05) :506-514
[13]   Molecular cytogenetic characterization of rhabdomyosarcoma cell lines [J].
Rodriguez-Perales, S ;
Martínez-Ramírez, A ;
de Andrés, SA ;
Valle, L ;
Urioste, M ;
Benítez, J ;
Cigudosa, JC .
CANCER GENETICS AND CYTOGENETICS, 2004, 148 (01) :35-43
[14]   Myogenin and MyoD1 expression in paediatric rhabdomyosarcomas [J].
Sebire, NJ ;
Malone, M .
JOURNAL OF CLINICAL PATHOLOGY, 2003, 56 (06) :412-416
[15]  
Sekhar MSM, 2000, J ORAL MAXIL SURG, V58, P1062
[16]  
Tintignac LA, 2001, B CANCER, V88, P545
[17]   Clinical relevance of molecular diagnosis in childhood rhabdomyosarcoma [J].
Tobar, A ;
Avigad, S ;
Zoldan, M ;
Mor, C ;
Goshen, Y ;
Zaizov, R .
DIAGNOSTIC MOLECULAR PATHOLOGY, 2000, 9 (01) :9-13