Sydenham's chorea: MRI and proton spectroscopy

被引：27
作者：
Castillo, M [1 ]
Kwock, L [1 ]
Arbelaez, A [1 ]
机构：
[1] Univ N Carolina, Sch Med, Dept Radiol, Chapel Hill, NC 27599 USA
来源：
NEURORADIOLOGY | 1999年 / 41卷 / 12期
关键词：
chorea; Sydenham's; magnetic resonance imaging; magnetic resonance spectroscopy;
D O I：
10.1007/s002340050872
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We present the MRI and proton spectroscopy findings in a child with clinical diagnosis of Sydenham's chorea. MRI showed high signal in the caudate nuclei and putamina on T2-weighted images. We believe that the spectra showed an abnormality in the number and/or function of neurons, lipids from cellular breakdown (cytolytic effect of antibodies), aminoacids (related to the presence of antibodies in the neostriatum), and sugars (also related to the presence of antibodies). The spectroscopy features correlate well with the histopathology and biochemistry of this rare disorder.
引用
收藏
页码：943 / 945
页数：3
相关论文
共 9 条
  • [1] Sydenham Chorea: Magnetic resonance imaging reveals permanent basal ganglia injury
    Emery, ES
    Vieco, PT
    [J]. NEUROLOGY, 1997, 48 (02) : 531 - 533
  • [2] Sydenham's chorea: Magnetic resonance imaging of the basal ganglia
    Giedd, JN
    Rapoport, JL
    Kruesi, MJP
    Parker, C
    Schapiro, MB
    Allen, AJ
    Leonard, HL
    Kaysen, D
    Dickstein, DP
    Marsh, WL
    Kozuch, PL
    Vaituzis, AC
    Hamburger, SD
    Swedo, SE
    [J]. NEUROLOGY, 1995, 45 (12) : 2199 - 2202
  • [3] HARFENIST EJ, 1993, HARPERS BIOCH, P673
  • [4] SYDENHAM CHOREA - CLINICAL, EEG, MRI AND SPECT FINDINGS IN THE EARLY STAGE OF THE DISEASE
    HEYE, N
    JERGAS, M
    HOTZINGER, H
    FARAHATI, J
    POHLAU, D
    PRZUNTEK, H
    [J]. JOURNAL OF NEUROLOGY, 1993, 240 (02) : 121 - 123
  • [5] ANTIBODIES REACTING WITH CYTOPLASM OF SUBTHALAMIC AND CAUDATE NUCLEI NEURONS IN CHOREA AND ACUTE RHEUMATIC-FEVER
    HUSBY, G
    VANDERIJN, I
    ZABRISKIE, JB
    ABDIN, ZH
    WILLIAMS, RC
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1976, 144 (04) : 1094 - 1110
  • [6] KIENZLE GD, 1991, AM J NEURORADIOL, V12, P73
  • [7] MRI IN HEMIBALLISMUS DUE TO SYDENHAM CHOREA
    KONAGAYA, M
    KONAGAYA, Y
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1992, 55 (03) : 238 - 239
  • [8] DETERMINATION OF METABOLITE AND NUCLEOTIDE CONCENTRATIONS IN PROLIFERATING LYMPHOCYTES BY H-1-NMR OF ACID-EXTRACTS
    SZE, DY
    JARDETZKY, O
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1054 (02) : 181 - 197
  • [9] TRAILL Z, 1995, DEV MED CHILD NEUROL, V37, P270
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