Sydenham's chorea: MRI and proton spectroscopy

被引：27

作者：

Castillo, M ^{[1
]}

Kwock, L ^{[1
]}

Arbelaez, A ^{[1
]}

机构：

[1] Univ N Carolina, Sch Med, Dept Radiol, Chapel Hill, NC 27599 USA

来源：

NEURORADIOLOGY | 1999年 / 41卷 / 12期

关键词：

chorea; Sydenham's; magnetic resonance imaging; magnetic resonance spectroscopy;

D O I：

10.1007/s002340050872

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We present the MRI and proton spectroscopy findings in a child with clinical diagnosis of Sydenham's chorea. MRI showed high signal in the caudate nuclei and putamina on T2-weighted images. We believe that the spectra showed an abnormality in the number and/or function of neurons, lipids from cellular breakdown (cytolytic effect of antibodies), aminoacids (related to the presence of antibodies in the neostriatum), and sugars (also related to the presence of antibodies). The spectroscopy features correlate well with the histopathology and biochemistry of this rare disorder.

引用

页码：943 / 945

页数：3

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