Neobacillamide A, a Novel Thiazole-Containing Alkaloid from the Marine Bacterium Bacillus vallismortis C89, Associated with South China Sea Sponge Dysidea avara

被引：41

作者：

Yu, Lu-Lu ^{[1
]}

Li, Zhen-Yu ^{[2
]}

Peng, Chong-Sheng ^{[3
]}

Li, Zhi-Yong ^{[1
]}

Guo, Yue-Wei ^{[2
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Life Sci & Biotechnol, Minist Educ, Key Lab Microbial Metab, Shanghai 200240, Peoples R China

[2] Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China

[3] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2009年 / 92卷 / 03期

关键词：

METABOLITES;

D O I：

10.1002/hlca.200800349

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel thiazole alkaloid, neobacillamide A (1), together with a known related one, bacillamide C (4), was isolated from the bacterium Bacillus vallismortis C89, associated with the South China Sea Sponge Dysidea avara. The structure of the new compound was elucidated on the basis of its spectroscopic data. A plausible biosynthetic pathway is proposed. Neobacillamide A represents the first example of a thiazole-carboxamide bearing a 2-phenylethylamine moiety.

引用

收藏

页码：607 / 612

页数：6

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