The relationship between optic disc area and open-angle glaucoma: The Baltimore eye survey

被引:0
|
作者
Quigley, HA
Varma, R
Tielsch, JM
Katz, J
Sommer, A
Gilbert, DL
机构
[1] Johns Hopkins Univ Hosp, Sch Med, Wilmer Inst, Glaucoma Serv, Baltimore, MD 21287 USA
[2] Johns Hopkins Univ Hosp, Sch Med, Wilmer Inst, Dana Ctr Prevent Ophthalmol, Baltimore, MD 21287 USA
[3] Johns Hopkins Sch Hyg & Publ Hlth, Dept Int Hlth, Baltimore, MD USA
[4] Univ So Calif, Doheny Eye Inst, Dept Ophthalmol, Los Angeles, CA USA
关键词
glaucoma; imaging; intraocular pressure; optic disc area; pathogenesis;
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To determine if eyes with larger optic disc area are more likely to have open-angle glaucoma or to have glaucoma at lower intraocular pressure (IOP). Methods: Data were collected from a population-based sample of adults residing in East Baltimore, consisting of demographic information, ocular examinations, automated and static/kinetic visual field tests, IOP as measured by applanation tonometry, and image analysis of the optic disc. Optic disc area was calculated using refractive error to correct magnification. Open-angle glaucoma was defined by visual field and optic disc criteria. One eye from each of 75 patients with glaucoma was compared to those of 3,518 subjects without glaucoma. Results: Although optic disc area was somewhat larger among patients with glaucoma than control subjects, in a regression model adjusting for age, gender, and race, the significance of this difference had a probability of 0.06. Among patients with glaucoma, disc area was not related to IOP level measured at study examination. Conclusion: Disc area is a weak risk factor for open-angle glaucoma. Disc area did not differ between patients with glaucoma who had lower IOP and those who had higher IOP among a group with glaucoma that were identified in a population survey.
引用
收藏
页码:347 / 352
页数:6
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