Evidence-based feeding strategies before and after the development of necrotizing enterocolitis

被引：59

作者：

Good, Misty ^{[1
,2
]}

Sodhi, Chhinder P. ^{[2
,3
]}

Hackam, David J. ^{[2
,3
]}

机构：

[1] Childrens Hosp Pittsburgh, Dept Pediat, Div Newborn Med, Pittsburgh, PA 15213 USA

[2] Univ Pittsburgh, Sch Med, Pittsburgh, PA 15260 USA

[3] Childrens Hosp Pittsburgh, Dept Surg, Div Pediat Surg, Pittsburgh, PA 15213 USA

来源：

EXPERT REVIEW OF CLINICAL IMMUNOLOGY | 2014年 / 10卷 / 07期

基金：

美国国家卫生研究院;

关键词：

amniotic fluid; breast milk; growth factors; innate immunity; necrotizing enterocolitis; prematurity; toll-like receptor 4; LOW-BIRTH-WEIGHT; EPIDERMAL-GROWTH-FACTOR; INNATE IMMUNE-SYSTEM; FORTIFIED HUMAN-MILK; LATE-ONSET SEPSIS; DONOR HUMAN-MILK; PRETERM INFANTS; RANDOMIZED-TRIAL; DOUBLE-BLIND; ARGININE SUPPLEMENTATION;

D O I：

10.1586/1744666X.2014.913481

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Necrotizing enterocolitis (NEC) is a devastating disease of premature infants and is associated with significant morbidity and mortality. While the pathogenesis of NEC remains incompletely understood, it is well established that the risk of disease is increased by the administration of infant formula and decreased by the administration of breast milk. This review will focus on the mechanisms by which breast milk may serve to protect against NEC, and will review the evidence regarding various feeding strategies that may be utilized before and after an episode of NEC.

引用

页码：875 / 884

页数：10

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