Chronic Spontaneous Urticaria Etiology and Pathogenesis

被引：96
作者：
Saini, Sarbjit S. [1 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Johns Hopkins Asthma & Allergy Ctr, Div Allergy & Clin Immunol, Baltimore, MD 21224 USA
来源：
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2014年 / 34卷 / 01期
基金：
美国国家卫生研究院;
关键词：
Chronic urticaria; Mast cells; Basophils; CHRONIC IDIOPATHIC URTICARIA; FC-EPSILON-RI; SERUM SKIN-TEST; AFFINITY IGE RECEPTOR; AUTOLOGOUS SERUM; HISTAMINE-RELEASE; ANTI-IGE; COLD URTICARIA; SEROLOGICAL MEDIATOR; AUTOIMMUNE URTICARIA;
D O I：
10.1016/j.iac.2013.09.012
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Urticaria affects individuals of all ages and is commonplace. Nearly 1 in 5 individuals will experience an episode of urticaria in their lifetime, while the chronic form of disease has an estimated annual prevalence of approximately 1% of the population. Given the similarity of chronic urticaria symptoms to those seen in patients suffering an allergic reaction, the condition often leads to a search for an external cause. In most cases, no external trigger factor is identified. At present several theories of pathogenesis exist, none of which is firmly established.
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页码：33 / +
页数：22
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