OBJECTIVE: To investigate the effect of postoperative gum chewing on bowel motility after laparoscopic gynecologic surgery. METHODS: In this randomized controlled trial, patients were allocated to either postoperative gum chewing every 2 hours for 15 minutes or standard postoperative care without gum chewing. The study's primary end points were time to first regular bowel sounds and time to first passage of flatus after surgery. Secondary end points were time of operation to first defecation, patient satisfaction concerning postoperative gum chewing, potential side effects of postoperative gum chewing, and potential effect of gum chewing on postoperative pain therapy. RESULTS: One hundred seventy-nine patients were included in this trial. We found a significantly shorter interval between surgery and passage of first flatus in the intervention group compared with the control group (median 6.2 hours compared with 8.1 hours; P=.002) and a significantly higher rate of regular bowel sounds 3 hours (76% compared with 47%; P<.001) and 5 hours (91% compared with 78%; P=.01) after surgery. Fewer opioid analgetics were administered to patients allocated to the intervention group (P=.02). There was no significant difference in time to first defecation between groups (median 26.3 hours compared with 29.0 hours, P=.165). Gum chewing was well tolerated and well accepted by patients, and no intervention-related side effects were observed. CONCLUSION: Gum chewing seems to have beneficial effects on bowel motility when used as an adjunct treatment in postoperative care after minimally invasive surgery. Gum chewing should be recommended to patients after gynecologic laparoscopic surgery.
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Crit Care Med, 150,Ximen St, Taizhou 317000, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Chen, Nanjin
Ji, Shuman
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Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Anesthesiol, Xian, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Ji, Shuman
Liu, Junfei
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Pathol, Taizhou, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Liu, Junfei
Wang, Liping
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Crit Care Med, 150,Ximen St, Taizhou 317000, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Wang, Liping
Chen, Fenglin
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Crit Care Med, 150,Ximen St, Taizhou 317000, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Chen, Fenglin
Zhu, Yanwu
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Pharm, Taizhou, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Zhu, Yanwu
Li, Jiao
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Crit Care Med, 150,Ximen St, Taizhou 317000, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Li, Jiao
Chen, Minjuan
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Crit Care Med, 150,Ximen St, Taizhou 317000, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Chen, Minjuan
Chen, Lingyang
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Crit Care Med, 150,Ximen St, Taizhou 317000, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Chen, Lingyang
Wang, Mingcang
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Crit Care Med, 150,Ximen St, Taizhou 317000, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Wang, Mingcang
He, Ruyi
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Crit Care Med, 150,Ximen St, Taizhou 317000, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
He, Ruyi
Mei, Xiaopeng
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Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Anesthesiol, Xian, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Mei, Xiaopeng
Zhang, Zhanqin
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Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Anesthesiol, Xian, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Zhang, Zhanqin
Jin, Shengwei
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Wenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou 325088, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Jin, Shengwei
Zheng, Jingming
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Crit Care Med, 150,Ximen St, Taizhou 317000, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
Zheng, Jingming
Jiang, Yongpo
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Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Crit Care Med, 150,Ximen St, Taizhou 317000, Peoples R ChinaWenzhou Med Univ, Affiliated Hosp 2, Dept Anesthesiol & Crit Care, Taizhou 325088, Peoples R China
机构:
Department of Surgery, Sahlgrenska University Hospital, GothenburgDepartment of Surgery, Sahlgrenska University Hospital, Gothenburg
Andersson T.
Bjerså K.
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Department of Medical and Health Sciences, Division of Nursing Science, University of Linköping, LinköpingDepartment of Surgery, Sahlgrenska University Hospital, Gothenburg
Bjerså K.
Falk K.
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Institute of Health and Care Sciences, Sahlgrenska Academy at Gothenburg University, GothenburgDepartment of Surgery, Sahlgrenska University Hospital, Gothenburg