Assessment and characterisation of post-COVID-19 manifestations

被引:331
作者
Kamal, Marwa [1 ]
Abo Omirah, Marwa [2 ]
Hussein, Amal [3 ]
Saeed, Haitham [4 ]
机构
[1] Fayoum Univ, Fac Pharm, Clin Pharm Dept, Al Fayyum, Egypt
[2] Fayoum Univ, Fac Med, Dept Neurol, Al Fayyum, Egypt
[3] Minia Univ, Fac Pharm, Dept Pharmaceut, Al Minya, Egypt
[4] Beni Suef Univ, Fac Pharm, Clin Pharm Dept, Bani Suwayf, Egypt
关键词
COVID‐ 19; fatigue; post‐ manifestations; pulmonary fibrosis; SURVIVORS; PNEUMONIA; FATIGUE;
D O I
10.1111/ijcp.13746
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Post-COVID-19 symptoms and diseases appeared on many survivors from COVID-19 which are similar to that of the post-severe acute respiratory syndrome (SARS) fatigue. Hence, the study aims to investigate and characterise the manifestations which appear after eradication of the coronavirus infection and its relation to disease severity. Method About 287 survivors from COVID-19 were included in the study, each received a questionnaire divided into three main parts starting from subjects' demographic data, data about the COVID-19 status and other comorbidities of the subject, and finally data about post-COVID-19 manifestations. Response surface plots were produced to visualise the link between several factors. Results Only 10.8% of all subjects have no manifestation after recovery from the disease while a large percentage of subjects suffered from several symptoms and diseases. The most common symptom reported was fatigue (72.8%), more critical manifestations like stroke, renal failure, myocarditis and pulmonary fibrosis were reported by a few percent of the subjects. There was a relationship between the presence of other comorbidities and severity of the disease. Also, the severity of COVID-19 was related to the severity of post-COVID-19 manifestations. Conclusion The post-COVID-19 manifestation is largely similar to the post-SARS syndrome. All subjects recovered from COVID-19 should undergo long-term monitoring for evaluation and treatment of symptoms and conditions that might be precipitated with the new coronavirus infection.
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