Where we missed? Middle East Respiratory Syndrome (MERS-CoV) epidemiology in Saudi Arabia; 2012-2019

被引:7
作者
Khan, Saman [1 ]
El Morabet, Rachida [2 ]
Khan, Roohul Abad [3 ]
Bindajam, Ahmad [4 ]
Alqadhi, Saeed [3 ]
Alsubih, Majed [3 ]
Khan, Nadeem Ahmad [5 ]
机构
[1] Integral Univ, Dept Civil Engn, Lucknow, Uttar Pradesh, India
[2] Hassan II Univ Casablanca, Dept Geog, LADES Lab, FLSH, Mohammadia, Morocco
[3] King Khalid Univ, Dept Civil Engn, Gureiger Campus,POB 860, Abha 61421, Saudi Arabia
[4] King Khalid Univ, Dept Architecture & Urban Planning, Abha, Saudi Arabia
[5] Jamia Millia Islamia, Dept Civil Engn, New Delhi, India
关键词
MERS-CoV epidemiology; Gender; Age group; Comorbid; Symptomatic; CORONAVIRUS; TRANSMISSION; INFECTION; RISK;
D O I
10.1016/j.scitotenv.2020.141369
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
MERS-CoV first case was reported on 23rd November 2012 in Saudi Arabia, Since, then MERS has remained on World Health Organization (WHO) Blueprint list and declared pandemic. This study was conducted on MERS lab confirmed cases reported to Ministry of Health, Saudi Arabia and WHO for year 2012-2019. The epidemiology was investigated based on infection rate, death rate, case fatality rate, Gender, Age group, and Medical conditions (Comorbid and Symptomatic). The overall median age of infected male was 58 years and of female was 45 years. While average mortality age in male was 60 years and of female was 65 years which is greater than the global average of 50 years. The results also report that specially after age of 40 years in both men and women, chances of infection are more while comorbidities increase the infection rate. The men are more susceptible to infection than women. In case of asymptomatic distribution trend was vice versa with 69.4% women and 30.6% in men. Second, most infected age group was reduced by 20 years in case of men with 47.37% infection for age group of 20-39 years. Thiswas also observed in age-group of 20-39 years for no comorbid cases (men (50%) & women (79%)). This explains MERS-CoV prevalence in Saudi Arabia, as young and healthy population were infected, and acted as carrier and on coming in contact with vulnerable population (Elderly, chronic and comorbid) transferred the infection. Hence, MERS-CoV outbreak kept on happening from time to time over past years. This finding might very well explain the exponential spread of Novel CoV-19 globally, as initial control measures required older people to stay indoors while younger generation brought infection from outside. Further studies are required for epidemiology analysis based on clusters, travel history and specific disease related mortality. (c) 2020 Elsevier B.V. All rights reserved.
引用
收藏
页数:7
相关论文
共 50 条
[21]   Middle East Respiratory Syndrome Coronavirus (MERS-CoV): State of the Science [J].
Mostafa, Ahmed ;
Kandeil, Ahmed ;
Shehata, Mahmoud ;
El Shesheny, Rabeh ;
Samy, Abdallah M. ;
Kayali, Ghazi ;
Ali, Mohamed A. .
MICROORGANISMS, 2020, 8 (07) :1-27
[22]   The epidemiology of Middle East respiratory syndrome coronavirus in the Kingdom of Saudi Arabia, 2012-2015 [J].
Alsahafi, Abdullah J. ;
Cheng, Allen C. .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2016, 45 :1-4
[23]   Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Dromedary Camels in Africa and Middle East [J].
Kandeil, Ahmed ;
Gomaa, Mokhtar ;
Nageh, Ahmed ;
Shehata, Mahmoud M. ;
Kayed, Ahmed E. ;
Sabir, Jamal S. M. ;
Abiadh, Awatef ;
Jrijer, Jamel ;
Amr, Zuhair ;
Abi Said, Mounir ;
Byarugaba, Denis K. ;
Wabwire-Mangen, Fred ;
Tugume, Titus ;
Mohamed, Nadira S. ;
Attar, Roba ;
Hassan, Sabah M. ;
Abdulaziz Linjawi, Sabah ;
Moatassim, Yassmin ;
Kutkat, Omnia ;
Mahmoud, Sara ;
Bagato, Ola ;
Abo Shama, Noura M. ;
El-Shesheny, Rabeh ;
Mostafa, Ahmed ;
Perera, Ranawaka A. P. M. ;
Chu, Daniel K. W. ;
Hassan, Nagla ;
Elsokary, Basma ;
Saad, Ahmed ;
Sobhy, Heba ;
El Masry, Ihab ;
McKenzie, Pamela P. ;
Webby, Richard J. ;
Peiris, Malik ;
Makonnen, Yilma J. ;
Ali, Mohamed A. ;
Kayali, Ghazi .
VIRUSES-BASEL, 2019, 11 (08)
[24]   Sero-prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) specific antibodies in dromedary camels in Tabuk, Saudi Arabia [J].
Harrath, Rafik ;
Abu Duhier, Faisel M. .
JOURNAL OF MEDICAL VIROLOGY, 2018, 90 (08) :1285-1289
[25]   A longitudinal study of Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels [J].
Abdelazim, Mohamed ;
Abdelkader, Rehab ;
Ali, Abdelhakim ;
Shahein, Momtaz A. ;
Tadesse, Zelalem ;
Saad, Ahmed ;
Mansour, Amal ;
Ali, Samah F. ;
Atea, Mohamed ;
Gardner, Emma ;
VonDobschuetz, Sophie ;
Morzaria, Subhash ;
Makonnen, Yilma ;
Lubroth, Juan ;
Sumption, Keith ;
ElMasry, Ihab ;
Zakaria, Tarek ;
Eid, Samah ;
Hatab, Eman Abo ;
Hagag, Naglaa M. ;
Yousef, Hend M. Y. ;
Emara, Mervate ;
Abdelwahed, Dina A. ;
Abdelmegeed, Hala K. ;
Hamdy, Mervat E. ;
Mansour, Othman N. O. ;
Guitian, Javier .
BMC VETERINARY RESEARCH, 2023, 19 (01)
[26]   Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Seropositive Camel Handlers in Kenya [J].
Kiyonga, Alice N. ;
Cook, Elizabeth A. J. ;
Okba, Nisreen M. A. ;
Kivali, Velma ;
Reusken, Chantal ;
Haagmans, Bart L. ;
Fevre, Eric M. .
VIRUSES-BASEL, 2020, 12 (04)
[27]   Therapeutic Options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection: How Close Are We? [J].
Ali S. Omrani ;
Ziad A. Memish .
Current Treatment Options in Infectious Diseases, 2015, 7 (3) :202-216
[28]   Some pathological observations on the naturally infected dromedary camels (Camelus dromedarius) with the Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia 2018-2019 [J].
Alnaeem, Abdelmohsen ;
Kasem, Samy ;
Qasim, Ibrahim ;
Al-Doweriej, Ali ;
Al-Houfufi, Ali ;
Alwazan, Abdulatif ;
Albadrani, Abdalaziz ;
Alshaammari, Khuzayyim ;
Refaat, Mohamed ;
Al-Shabebi, Abdulkareem ;
Hemida, Maged Gomaa .
VETERINARY QUARTERLY, 2020, 40 (01) :190-197
[29]   Middle East respiratory syndrome-coronavirus (MERS-CoV): A new threat? [J].
Stafylidis, S. ;
Kafkia, T. ;
Xatzigeorgiadou, M. .
ARCHIVES OF HELLENIC MEDICINE, 2014, 31 (04) :423-426
[30]   Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir [J].
Hamzah A. Mohd ;
Jaffar A. Al-Tawfiq ;
Ziad A. Memish .
Virology Journal, 13