High-resolution diffusion-weighted imaging identifies ischemic lesions in a majority of transient ischemic attack patients

被引：19
|
作者：
Hotter, Benjamin [1 ,2 ]
Galinovic, Ivana [1 ]
Kunze, Claudia [1 ]
Brunecker, Peter [1 ,3 ]
Jungehulsing, Gerhard J. [1 ,4 ]
Villringer, Arno [1 ,5 ]
Endres, Matthias [1 ,2 ,3 ,5 ,6 ,7 ]
Villringer, Kersten [1 ,2 ]
Fiebach, Jochen B. [1 ]
机构：
[1] Charite Univ Med Berlin, Ctr Stroke Res Berlin, Berlin, Germany
[2] Charite Univ Med Berlin, Klin & Hsch Ambulanz Neurol, Berlin, Germany
[3] Berlin Inst Hlth, Berlin, Germany
[4] Jewish Hosp, Dept Neurol, Berlin, Germany
[5] Max Planck Inst Human Cognit & Brain Sci, Leipzig, Germany
[6] German Ctr Cardiovasc Res DZHK, Berlin, Germany
[7] German Ctr Neurodegenerat Dis DZNE, Berlin, Germany
来源：
ANNALS OF NEUROLOGY | 2019年 / 86卷 / 03期
关键词：
MRI ABNORMALITIES; STROKE; REVERSAL;
D O I：
10.1002/ana.25551
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Transient ischemic attack (TIA) is defined as focal neurological deficit caused by ischemia resolving within 24 hours. In a secondary analysis of a large monocentric cohort of 446 TIA patients, we explored the frequency and determinants of diffusion-weighted imaging (DWI) lesions on high-resolution magnetic resonance imaging. Overall, 240 (54%) of all TIA patients presented with DWI lesions. These patients had higher National Institute of Health Stroke Scale and ABCD2 scores and presented more frequently with vessel occlusion and perfusion deficits, but had similar functional outcome at 3 months. Taken together, high-resolution DWI provides evidence of ischemic brain injury in the majority of TIA patients. ANN NEUROL 2019
引用
收藏
页码：452 / 457
页数：6
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