Pharmacology Activity and Quercetin content of Mirabilis jalapa L.

"Pharmacology Activity and Quercetin content of Mirabilis jalapa L." Mirabilis jalapa (Nyctagi-naceae), popularly known in Brazil as "bonina" or "maravilha", is popularly used to treat infections, inflammations and pains. The crude extract ethanolic (70%) was prepared by maceration and fractionated with organic solvents of increasing polarity (hexane, dichloromethane, ethyl acetate and butanol). The best answer to the antimicrobial activity were obtained for Staphylococcus aureus with the dichloromethane fraction and Saccharomyces cerevisiae with ethyl acetate fraction. The extracts and fractions showed antioxidant activity by the method of DPPH, where the leaf ethyl acetate and butanol fractions showed excellent antioxidant activity with IC50 of 20.40 mu g/ml and 25.41 mu g/ml, respectively. The content of quercetin (0,19%) was determined in extracts from the leaves of liquid chromatography with high efficiency. The leaf hexanic fraction proved to be highly toxic front of Artemia salina with a LC50 of 1.27 mu g/ml.