Biosynthesis of oosponol and oospoglycol elucidated by C-13 NMR

被引：10
作者：
Sonnenbichler, J
Sonnenbichler, I
Schwarz, D
机构：
[1] Max Planck Inst. für Biochemie, 82152 Martinsried, Am Klopferspitz
来源：
PHYTOCHEMISTRY | 1997年 / 44卷 / 02期
关键词：
Gloeophyllum abietinum; fungal metabolites; oosponol; oospoglycol; biosyntheses; C-13; NMR;
D O I：
10.1016/S0031-9422(96)00469-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The biosynthesis of the antibiotic metabolities oosponol and oospoglycol by the fungus Gloeophyllum abietinum has been analysed using C-13-labelled acetate, malonate, serine and formate as precursors and C-13 NMR as the analytical method. The polyketide pathway could be confirmed. One carbon of the isocoumarin ring originates from serine. Copyright (C) 1996 Elsevier Science
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页码：267 / 269
页数：3
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