Association between suicide attempts in south Brazilian depressed patients with the serotonin transporter polymorphism

被引：18

作者：

Segal, Jair

Pujol, Clarissa

Birck, Alan

Manfro, Gisele Gus

Leistner-Segal, Sandra

机构：

[1] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Gen Med Serv, Post Grad Program Med Sci Psychiat, BR-90035903 Porto Alegre, RS, Brazil

[2] Hosp Pronto Socorro Porto Alegre, Porto Alegre, RS, Brazil

[3] Hosp Clin Porto Alegre, Psychiat Serv, BR-90035903 Porto Alegre, RS, Brazil

[4] Complexo Hosp Santa Casa Porto Alegre, Res Support Unit, Porto Alegre, RS, Brazil

来源：

PSYCHIATRY RESEARCH | 2006年 / 143卷 / 2-3期

关键词：

suicide attempt; serotonin transporter gene (5-HTT); polymorphism; serotonin transporter gene linked polymorphic region; (5-HTTLPR); depression;

D O I：

10.1016/j.psychres.2005.03.008

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

A polyrnorphism in the serotonin transporter gene (5-HTTLPR) is being studied for association with suicidal behavior. We verified the relationship between the frequencies of the 5-HTTLPR alleles in 84 depressed patients with suicide attempts compared with 152 controls. We found a higher risk for suicide behavior among depressed patients bearing SS or LS genotypes. (c) 2005 Elsevier Ireland Ltd. All rights reserved.

引用

页码：289 / 291

页数：3

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