Fluctuating hydrodynamics of multicomponent membranes with embedded proteins

被引：29

作者：

Camley, Brian A. ^{[1
,2
,3
]}

Brown, Frank L. H. ^{[3
,4
]}

机构：

[1] Univ Calif San Diego, Dept Phys, La Jolla, CA 92093 USA

[2] Univ Calif San Diego, Ctr Theoret Biol Phys, La Jolla, CA 92093 USA

[3] Univ Calif Santa Barbara, Dept Phys, Santa Barbara, CA 93106 USA

[4] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

来源：

JOURNAL OF CHEMICAL PHYSICS | 2014年 / 141卷 / 07期

基金：

美国国家科学基金会;

关键词：

SINGLE-PARTICLE TRACKING; IMMERSED BOUNDARY METHOD; LIPID-BILAYER MEMBRANES; BROWNIAN-MOTION; VESICLE MEMBRANES; PHASE-SEPARATION; LIQUID DOMAINS; HYBRID LIPIDS; FORCE-FIELD; DIFFUSION;

D O I：

10.1063/1.4892802

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A simulation method for the dynamics of inhomogeneous lipid bilayer membranes is presented. The membrane is treated using stochastic Saffman-Delbruck hydrodynamics, coupled to a phase-field description of lipid composition and discrete membrane proteins. Multiple applications are considered to validate and parameterize the model. The dynamics of membrane composition fluctuations above the critical point and phase separation dynamics below the critical point are studied in some detail, including the effects of adding proteins to the mixture. (C) 2014 AIP Publishing LLC.

引用

页数：27

共 140 条

[1] SELF-DIFFUSION OF INTERACTING MEMBRANE-PROTEINS [J].