Failure of Researchers, Reviewers, Editors, and the Media to Understand Flaws in Cancer Screening Studies Application to an Article in Cancer

被引：17

作者：

Berry, Donald A. ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Biostat, Houston, TX 77030 USA

来源：

CANCER | 2014年 / 120卷 / 18期

关键词：

cancer screening; observational studies; screening mammography; lead-time bias; length bias; randomized screening trials; efficacy of screening mammography by age; BREAST-CANCER; FOLLOW-UP; AGE; 40; MAMMOGRAPHY; MORTALITY; BENEFITS; WOMEN; TIME;

D O I：

10.1002/cncr.28795

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Observational studies present inferential challenges. These challenges are acute in cancer screening studies, in which lead-time and length biases are ever present. These biases can make any study worthless. Moreover, a flawed study's impact on the public can be deleterious when its conclusions are publicized by a naive media. Flawed studies can also make the public learn to be wary of any article or reports of articles claiming to be scientific. Here, the author addresses these and related issues in the context of a study published in Cancer. (C) 2014 American Cancer Society.

引用

页码：2784 / 2791

页数：8

共 23 条

[1]

[Anonymous], NY TIMES

[2]

[Anonymous], GUARDIAN

[3]

[Anonymous], 2002, CHICAGO TRIBUNE 0806

[4] Mammography before diagnosis among women age 80 years and older with breast cancer [J].

Badgwell, Brian D. ;

Giordano, Sharon H. ;

Duan, Zhigang Z. ;

Fang, Shenying ;

Bedrosian, Isabelle ;

Kuerer, Henry M. ;

Singletary, S. Eva ;

Hunt, Kelly K. ;

Hortobagyi, Gabriel N. ;

Babiera, Gildy .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (15) :2482-2488

[5] The screening mammography paradox: better when found, perhaps better not to find [J].

Berry, D. A. .

BRITISH JOURNAL OF CANCER, 2008, 98 (11) :1729-1730

[6] Benefits and risks of screening mammography for women in their forties: A statistical appraisal [J].

Berry, DA .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1998, 90 (19) :1431-1439

[7] Effect of screening and adjuvant therapy on mortality from breast cancer [J].

Berry, DA ;

Cronin, KA ;

Plevritis, SK ;

Fryback, DG ;

Clarke, L ;

Zelen, M ;

Mandelblatt, JS ;

Yakovlev, AY ;

Habbema, JDF ;

Feuer, EJ .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (17) :1784-1792

[8]

Berry DA, 1994, CHANCE, V4, P9

[9] The science of doping [J].

Berry, Donald A. .

NATURE, 2008, 454 (7205) :692-693

[10] Breast cancer screening: Controversy of impact [J].

Berry, Donald A. .

BREAST, 2013, 22 :S73-S76

← 1 2 3 →