Spectrophotometric determination of Buclizine as hydrochloride (BUCZ) using I2/PMAP-SAc, AM/PTC and PMA/cobalt(II)/EDTA

被引：0

作者：

Annapurna, V. ^{[2
]}

Jyothi, G. ^{[2
]}

Nagalakshmi, V. ^{[2
]}

Sailaja, B. B. V. ^{[1
]}

机构：

[1] Andhra Univ, Dept Inorgan & Analyt Chem, Visakhapatnam 530003, Andhra Pradesh, India

[2] St Theresas Coll Women, Dept Chem, Eluru 534003, Andhra Pradesh, India

来源：

JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2009年 / 86卷 / 04期

关键词：

Estimation; Buclizine; precipitating agent; charge transfer complex; THIOXANTHENE DERIVATIVES; FLUOROMETRIC-DETERMINATION; MASS-SPECTROMETRY; DOSAGE FORMS; CHROMATOGRAPHY; FLUIDS; DRUGS;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Simple, accurate and reproducible UV spectrophotometric methods were established for the assay of BUCZ based on the formation of precipitation, charge transfer and redox products. Precipitation/charge transfer complex formation of the BUCZ with I-2/p-N-methyl amino phenol sulphate (PMAP)-sulphanilic acid (SAc) by Method A, the precipitation/complex formation with ammonium molybdate (AM)/potassium thiocyanate (PTC) by Method B and precipitation/redox reaction of BUCZ with phosphomolybdic acid (PMA)/Co-II/EDTA by Method C were proposed. Determination of BUCZ in bulk form and in pharmaceutical formulations were also incorporated.

引用

页码：358 / 363

页数：6

共 19 条

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