Ligand-Free Pd/C-Catalyzed One-Pot, Three-Component Synthesis of Aryl-Substituted Benzimidazoles by Hydrogen-Transfer and Suzuki Reactions in Water

被引：22

作者：

Xu, Chen ^{[1
]}

Xiao, Zhi-Qiang ^{[2
]}

Li, Hong-Mei ^{[1
]}

Han, Xin ^{[2
]}

Wang, Zhi-Qiang ^{[1
]}

Fu, Wei-Jun ^{[1
]}

Ji, Bao-Ming ^{[1
]}

Hao, Xin-Qi ^{[2
]}

Song, Mao-Ping ^{[2
]}

机构：

[1] Luoyang Normal Univ, Coll Chem & Chem Engn, Luoyang 471022, Henan, Peoples R China

[2] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450001, Henan, Peoples R China

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 2015卷 / 34期

关键词：

Multicomponent reactions; Hydrogen transfer; Cross-coupling; Palladium; Nitrogen heterocycles; ENVIRONMENTALLY BENIGN OXIDATION; MULTICOMPONENT REACTIONS; COUPLING REACTIONS; SOLVENT; COMPLEXES; EFFICIENT; ALCOHOLS; DERIVATIVES; ALKYLATION; BENZAZOLES;

D O I：

10.1002/ejoc.201501169

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient protocol for the ligand-free and heterogeneous Pd/C-catalyzed one-pot, three-component synthesis of aryl-substituted benzimidazoles from benzyl alcohols by using water as the solvent was developed. The reaction involves hydrogen-transfer and Suzuki reactions. This method is quite convenient and environmentally friendly.

引用

页码：7427 / 7432

页数：6

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