Enantioselective synthesis of pyranofuranone moieties of manoalide and cacospongionolide B by enzymatic and chemical approach

被引：18

作者：

De Rosa, M ^{[1
]}

Soriente, A ^{[1
]}

Sodano, G ^{[1
]}

Scettri, A ^{[1
]}

机构：

[1] Univ Salerno, Dipartimento Chim, I-84081 Baronissi, Italy

来源：

TETRAHEDRON | 2000年 / 56卷 / 14期

关键词：

aldol reaction; asymmetric synthesis; enzyme catalysis; 1,3-dioxin-4-ones;

D O I：

10.1016/S0040-4020(00)00122-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two synthetic sequences leading to the pyranofuranone moieties of Manoalide and Cacospongionolide B in enantiomerically enriched forms are reported. The key steps involve either an enantioselective aldol condensation or an enzymatic resolution. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：2095 / 2102

页数：8