A meta-analysis on selective versus comprehensive neck dissection in oral squamous cell carcinoma patients with clinically node-positive neck

被引：42

作者：

Liang, Lizhong ^{[1
]}

Zhang, Tonghan ^{[2
]}

Kong, Qianying ^{[3
]}

Liang, Jun ^{[1
]}

Liao, Guiqing ^{[4
]}

机构：

[1] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Oral & Maxillofacial Surg, Zhuhai 519000, Guangdong, Peoples R China

[2] Sun Yat Sen Univ, Affiliated Zhongshan Hosp, Dept Stomatol, Zhongshan 528400, Guangdong, Peoples R China

[3] Zhuhai Stomatol Hosp, Zhuhai 519000, Guangdong, Peoples R China

[4] Sun Yat Sen Univ, Guanghua Sch Stomatol, Dept Oral & Maxillofacial Surg, Guangzhou 510000, Guangdong, Peoples R China

来源：

ORAL ONCOLOGY | 2015年 / 51卷 / 12期

基金：

中国国家自然科学基金;

关键词：

Meta-analysis; Selective neck dissection; Oral squamous cell carcinoma; Clinically node-positive neck; SKIP METASTASES; POSTERIOR TRIANGLE; LEVEL-IV; MANAGEMENT; CANCER; HEAD; RATIONALE; TONGUE;

D O I：

10.1016/j.oraloncology.2015.10.005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Objective: Properly management of cervical lymph node metastases is a critical treatment for patients with oral squamous cell carcinoma (OSCC). However there is no consensus on the optimal treatment for oral cancer patients with clinically node-positive (cN+) neck. This study aims to access the feasibility of selective neck dissection in oral cancer patients with cN+ neck. Method: We searched PubMed and EMBASE up to April 2015 to identify the studies which compared selective neck dissection (SND) with comprehensive neck dissection (CND) in OSCC patients with cN+ neck. Data were extracted by two authors. The meta-analysis was conducted with regional recurrence and disease specific death as primary endpoints. Result: Five studies with a total of 443 patients met our inclusion criteria. No significant difference was found regarding regional recurrence, disease specific death or overall death between the SND and CND group. Conclusion: These findings suggest that cN+ OSCC patients treated with SND in conjunction with adjuvant therapy got comparable clinical outcome to CND. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：1076 / 1081

页数：6

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