Metabolic syndrome in Saudi women with low bone mineral density

Background. - Metabolic syndrome (MetS) is the world's major public health problem. Objectives. - Assessment of metabolic syndrome impact on bone mineral density (BMD) among Saudi menopausal women in Eastern Province - Saudi Arabia. Material and Methods. - It's a case control study and 380 menopausal Saudi women were selected through stratified random sampling; they are divided into 190 cases with osteoporosis and 190 without osteoporosis. BMD at the total hip were determined using dual-energy X-ray absorptiometry (DEXA). The T score was calculated, the relationship between the risk factors of MetS and bone mineral density were analyzed by statistical methods. Results. - Prevalence of MetS was substantially higher among osteoprotic women. The MetS is significantly correlated with bone mineral density (r=0.08, P=0.05). The occurrence of MetS was associated with increased osteoporosis among Saudi women (B=0.004; 0.05) after adjustment of confounders. The presence of obesity (component of MetS) was significantly associated with increased odds of Bone marrow density among women (OR 2.56, 95% CI, 2.22-3.44, P=0.030) after adjustment of confounders. Conclusion. - MetS was significantly associated with an osteoporosis in Saudi women.