Foot-and-mouth disease: Technical and political challenges to eradication

被引:29
|
作者
Smith, Mark T. [1 ]
Bennett, Anthony M. [1 ]
Grubman, Marvin J. [2 ]
Bundy, Bradley C. [1 ]
机构
[1] Brigham Young Univ, Dept Chem Engn, Provo, UT 84602 USA
[2] USDA ARS, Plum Isl Anim Dis Ctr, North Atlantic Area, Greenport, NY 11944 USA
关键词
Foot-and-mouth; Disease; Virus; Vaccine; Outbreak; VIRUS; PATHOGENESIS; VACCINATION; OUTBREAK; VACCINES; LESSONS; TRANSMISSION; EXPERIENCE; ECONOMICS; HISTORY;
D O I
10.1016/j.vaccine.2014.04.038
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Foot-and-mouth disease (FMD) is a highly-contagious livestock disease with global socioeconomic ramifications. The disease negatively impacts both individual farmers through reduced herd viability and nations through trade restrictions of animals and animal derivatives. Vaccines for FMD prevention have existed for over 70 years, yet the disease remains enzootic in a large percentage of the globe. FMD persistence is due in part to technical limitations of historic and current vaccine technologies. There also exist many socioeconomic and political barriers to global FMD eradication. Here we highlight the barriers to eradication and discuss potential avenues toward FMD eradication. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3902 / 3908
页数:7
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