Natural products and complementary therapies for chemotherapy-induced peripheral neuropathy: A systematic review

被引：104

作者：

Brami, Cloe ^{[1
]}

Bao, Ting ^{[2
]}

Deng, Gary ^{[3
]}

机构：

[1] Hop St Louis, APHP, Dept Oncol, 1 Ave Claude Vellefaux, F-75010 Paris, France

[2] Mem Sloan Kettering Canc Ctr, Integrat Med & Breast Oncol Serv, 1429 First Ave, New York, NY 10021 USA

[3] Mem Sloan Kettering Canc Ctr, Integrat Med Serv, 1429 First Ave, New York, NY 10021 USA

来源：

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2016年 / 98卷

关键词：

Chemotherapy; Peripheral neuropathy; Platinum drugs; Natural products; Dietary supplements; Complementary therapies; Integrative medicine; Randomized controlled trials; ALPHA-LIPOIC ACID; QUALITY-OF-LIFE; OXALIPLATIN-RELATED NEUROTOXICITY; COLORECTAL-CANCER SURVIVORS; PLACEBO-CONTROLLED TRIAL; ACETYL-L-CARNITINE; DOUBLE-BLIND; MAGNESIUM PROPHYLAXIS; ALTERNATIVE MEDICINE; DIABETIC-NEUROPATHY;

D O I：

10.1016/j.critrevonc.2015.11.014

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chemotherapy-induced peripheral neuropathy (CIPN) is a serious dose-limiting side-effect without any FDA-approved treatment option. Prior reviews focus mostly on pharmacological interventions, but non pharmaceutical interventions have also been evaluated. A Web of Science and PubMed database search to identify relevant RCTs from January 2005 to May 2015 included the terms: CIPN, cancer; and supplements, vitamin E, goshajinkigan, kampo, acetyl-L-carnitine, carnitine, alpha-lipoic acid, omega-3, glutamine, or glutamate; or massage, acupuncture, mind-body practice, yoga, meditation, Tai-Chi, physical activity, or exercise. Of 1465 publications screened, 12 RCTs evaluated natural products and one evaluated electroacupuncture. Vitamin E may help prevent CIPN. L-Glutamine, goshajinkigan, and omega-3 are also promising. Acetyl-L-carnitine may worsen CIPN and alpha-lipoic acid activity is unknown. Electroacupuncture was not superior to placebo. No RCTs were published regarding other complementary therapies, although some studies mention positive incidental findings. Natural products and complementary therapies deserve further investigation, given the lack of effective CIPN interventions. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

引用

页码：325 / 334

页数：10

共 81 条

[21] Survivorship: Healthy Lifestyles, Version 2.2014 [J].

Denlinger, Crystal S. ;

Ligibel, Jennifer A. ;

Are, Madhuri ;

Baker, K. Scott ;

Demark-Wahnefried, Wendy ;

Dizon, Don ;

Friedman, Debra L. ;

Goldman, Mindy ;

Jones, Lee ;

King, Allison ;

Ku, Grace H. ;

Kvale, Elizabeth ;

Langbaum, Terry S. ;

Leonardi-Warren, Kristin ;

McCabe, Mary S. ;

Melisko, Michelle ;

Montoya, Jose G. ;

Mooney, Kathi ;

Morgan, Mary Ann ;

Moslehi, Javid J. ;

O'Connor, Tracey ;

Overholser, Linda ;

Paskett, Electra D. ;

Peppercorn, Jeffrey ;

Raza, Muhammad ;

Rodriguez, M. Alma ;

Syrjala, Karen L. ;

Urba, Susan G. ;

Wakabayashi, Mark T. ;

Zee, Phyllis ;

McMillian, Nicole R. ;

Freedman-Cass, Deborah A. .

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2014, 12 (09) :1222-1237

[22] Neuropathic pain in cancer [J].

Fallon, M. T. .

BRITISH JOURNAL OF ANAESTHESIA, 2013, 111 (01) :105-111

[23] Electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy in multiple myeloma: a feasibility study [J].

Garcia, M. Kay ;

Cohen, Lorenzo ;

Guo, Ying ;

Zhou, Yuhong ;

You, Bing ;

Chiang, Joseph ;

Orlowski, Robert Z. ;

Weber, Donna ;

Shah, Jatin ;

Alexanian, Raymond ;

Thomas, Sheeba ;

Romaguera, Jorge ;

Zhang, Liang ;

Badillo, Maria ;

Chen, Yiming ;

Wei, Qi ;

Lee, Richard ;

Delasalle, Kay ;

Green, Vivian ;

Wang, Michael .

JOURNAL OF HEMATOLOGY & ONCOLOGY, 2014, 7

[24] Omega-3 fatty acids are protective against paclitaxel-induced peripheral neuropathy: A randomized double-blind placebo controlled trial [J].

Ghoreishi, Zohreh ;

Esfahani, Ali ;

Djazayeri, Abolghasem ;

Djalali, Mahmoud ;

Golestan, Banafsheh ;

Ayromlou, Hormoz ;

Hashemzade, Shahriar ;

Jafarabadi, Mohammad Asghari ;

Montazeri, Vahid ;

Keshavarz, Seyed Ali ;

Darabi, Masoud .

BMC CANCER, 2012, 12

[25] Oral alpha-lipoic acid to prevent chemotherapy-induced peripheral neuropathy: a randomized, double-blind, placebo-controlled trial [J].

Guo, Ying ;

Jones, Desiree ;

Palmer, J. Lynn ;

Forman, Arthur ;

Dakhil, Shaker R. ;

Velasco, Maria R. ;

Weiss, Matthias ;

Gilman, Paul ;

Mills, G. M. ;

Noga, Stephen J. ;

Eng, Cathy ;

Overman, Michael J. ;

Fisch, Michael J. .

SUPPORTIVE CARE IN CANCER, 2014, 22 (05) :1223-1231

[26] A review of relative dose intensity and survival in patients with metastatic solid tumors [J].

Havrilesky, Laura J. ;

Reiner, Maureen ;

Morrow, Phuong Khanh ;

Watson, Holly ;

Crawford, Jeffrey .

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2015, 93 (03) :203-210

[27] Strength and endurance training in the treatment of lung cancer patients in stages IIIA/IIIB/IV [J].

Henke, C. C. ;

Cabri, J. ;

Fricke, L. ;

Pankow, W. ;

Kandilakis, G. ;

Feyer, P. C. ;

de Wit, M. .

SUPPORTIVE CARE IN CANCER, 2014, 22 (01) :95-101

[28] Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline [J].

Hershman, Dawn L. ;

Lacchetti, Christina ;

Dworkin, Robert H. ;

Smith, Ellen M. Lavoie ;

Bleeker, Jonathan ;

Cavaletti, Guido ;

Chauhan, Cynthia ;

Gavin, Patrick ;

Lavino, Antoinette ;

Lustberg, Maryam B. ;

Paice, Judith ;

Schneider, Bryan ;

Smith, Mary Lou ;

Smith, Tom ;

Terstriep, Shelby ;

Wagner-Johnston, Nina ;

Bak, Kate ;

Loprinzi, Charles L. .

JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (18) :1941-+

[29] Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy [J].

Hershman, Dawn L. ;

Unger, Joseph M. ;

Crew, Katherine D. ;

Minasian, Lori M. ;

Awad, Danielle ;

Moinpour, Carol M. ;

Hansen, Lisa ;

Lew, Danika L. ;

Greenlee, Heather ;

Fehrenbacher, Louis ;

Wade, James L., III ;

Wong, Siu-Fun ;

Hortobagyi, Gabriel N. ;

Meyskens, Frank L. ;

Albain, Kathy S. .

JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (20) :2627-+

[30] How Many Cancer Patients Use Complementary and Alternative Medicine: A Systematic Review and Metaanalysis [J].

Horneber, Markus ;

Bueschel, Gerd ;

Dennert, Gabriele ;

Less, Danuta ;

Ritter, Erik ;

Zwahlen, Marcel .

INTEGRATIVE CANCER THERAPIES, 2012, 11 (03) :187-203

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