Enrich the environment to empower the brain

被引:250
作者
Sale, Alessandro [1 ]
Berardi, Nicoletta [2 ,3 ]
Maffei, Larnberto [1 ,3 ]
机构
[1] Scuola Normale Super Pisa, Neurobiol Lab, I-56100 Pisa, Italy
[2] Univ Florence, Dipartimento Psicol, I-50100 Florence, Italy
[3] CNR, Inst Neurosci, I-56100 Pisa, Italy
关键词
ADULT VISUAL-CORTEX; GROWTH-FACTOR-I; OCULAR DOMINANCE PLASTICITY; GENE-EXPRESSION; CRITICAL-PERIOD; MONOCULAR DEPRIVATION; DEPENDENT PLASTICITY; FUNCTIONAL RECOVERY; SYSTEM DEVELOPMENT; MEMORY DEFICITS;
D O I
10.1016/j.tins.2008.12.004
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Environmental enrichment (EE) has long been exploited to investigate the influence of the environment on brain structure and function. Robust morphological and functional effects elicited by EE at the neuronal level have been reported to be accompanied by improvements in cognitive performance. Recently, EE has been shown to accelerate the development of the visual system and to enhance visual-cortex plasticity in adulthood. These new findings highlight the potential of EE as a promising non-invasive strategy to ameliorate deficits in the maturation of the nervous system and to promote recovery of normal sensory functions in pathological conditions affecting the adult brain.
引用
收藏
页码:233 / 239
页数:7
相关论文
共 69 条
[1]  
BARO JA, 1990, INVEST OPHTH VIS SCI, V31, P1405
[2]   Environmental enrichment prevents effects of dark-rearing in the rat visual cortex [J].
Bartoletti, A ;
Medini, P ;
Berardi, N ;
Maffei, L .
NATURE NEUROSCIENCE, 2004, 7 (03) :215-216
[3]   EFFECT OF THE RICHNESS OF THE ENVIRONMENT ON THE CAT VISUAL-CORTEX [J].
BEAULIEU, C ;
COLONNIER, M .
JOURNAL OF COMPARATIVE NEUROLOGY, 1987, 266 (04) :478-494
[4]   Long-term continuous, but not daily, environmental enrichment reduces spatial memory decline in aged male mice [J].
Bennett, JC ;
McRae, PA ;
Levy, LJ ;
Frick, KM .
NEUROBIOLOGY OF LEARNING AND MEMORY, 2006, 85 (02) :139-152
[5]   Molecular basis of plasticity in the visual cortex [J].
Berardi, N ;
Pizzorusso, T ;
Ratto, GM ;
Maffei, L .
TRENDS IN NEUROSCIENCES, 2003, 26 (07) :369-378
[6]   Critical periods during sensory development [J].
Berardi, N ;
Pizzorusso, T ;
Maffei, L .
CURRENT OPINION IN NEUROBIOLOGY, 2000, 10 (01) :138-145
[7]  
Berardi N, 2007, J ALZHEIMERS DIS, V11, P359
[8]   EFFECTS OF DARK-REARING ON THE DEVELOPMENT OF AREA-18 OF THE CATS VISUAL-CORTEX [J].
BLAKEMORE, C ;
PRICE, DJ .
JOURNAL OF PHYSIOLOGY-LONDON, 1987, 384 :293-309
[9]   Acceleration of visual system development by environmental enrichment [J].
Cancedda, L ;
Putignano, E ;
Sale, A ;
Viegi, A ;
Berardi, N ;
Maffei, L .
JOURNAL OF NEUROSCIENCE, 2004, 24 (20) :4840-4848
[10]  
Carro E, 2000, J NEUROSCI, V20, P2926