Highly regioselective palladium-catalyzed condensation of terminal acetylenes with 2,5-diiodobenzoic acid

被引：13
|
作者：
Balavoine, F
Madec, D
Mioskowski, C [1 ]
机构：
[1] CEA Saclay, Serv Mol Marquees, DSV, DSM, F-91191 Gif Sur Yvette, France
[2] Univ Strasbourg 1, CNRS, Lab Synth Bioorgan, F-67401 Illkirch, France
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 48期
关键词：
alkynes; aryl halides; Sonogashira reaction; regioselection;
D O I：
10.1016/S0040-4039(99)01697-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium-catalyzed coupling reactions between terminal alkynes and 2,5-diiodobenzoic acid have been shown to be highly regioselective, giving a rapid and efficient route for the synthesis of disymmetric 2,5-bis ethynyl benzoic acid derivatives. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：8351 / 8354
页数：4
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