Highly regioselective palladium-catalyzed condensation of terminal acetylenes with 2,5-diiodobenzoic acid

被引：13

作者：

Balavoine, F

Madec, D

Mioskowski, C ^{[1
]}

机构：

[1] CEA Saclay, Serv Mol Marquees, DSV, DSM, F-91191 Gif Sur Yvette, France

[2] Univ Strasbourg 1, CNRS, Lab Synth Bioorgan, F-67401 Illkirch, France

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 48期

关键词：

alkynes; aryl halides; Sonogashira reaction; regioselection;

D O I：

10.1016/S0040-4039(99)01697-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed coupling reactions between terminal alkynes and 2,5-diiodobenzoic acid have been shown to be highly regioselective, giving a rapid and efficient route for the synthesis of disymmetric 2,5-bis ethynyl benzoic acid derivatives. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：8351 / 8354

页数：4

共 7 条

[1] SYNTHESIS OF ARYL-SUBSTITUTED AND VINYL-SUBSTITUTED ACETYLENE DERIVATIVES BY USE OF NICKEL AND PALLADIUM COMPLEXES [J].