Absolute Configurational Assignment in Chiral Compounds through Vibrational Circular Dichroism (VCD) Spectroscopy

被引：0
作者：
Uncuta, Cornelia [1 ]
Ion, Simona [1 ]
Gherase, Dragos [1 ]
Bartha, Emeric [1 ]
Teodorescu, Florina [1 ]
Filip, Petru [1 ]
机构：
[1] Romanian Acad, CD Nenitzescu Ctr Organ Chem, Bucharest 060023, Romania
来源：
REVISTA DE CHIMIE | 2009年 / 60卷 / 01期
关键词：
VCD spectroscopy; absolute configuration; ab initio DFT calculations; FUNCTIONAL THEORY CALCULATIONS; ASYMMETRIC-SYNTHESIS; SOLUTION CONFORMATION; PREDOMINANT CONFORMATIONS; CHIROPTICAL PROPERTIES; RECEPTOR ANTAGONIST; ACID-DERIVATIVES; NATURAL-PRODUCTS; CHANNEL BLOCKER; DONOR-ACCEPTOR;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Trends and perspectives of the IR/VCD chiroptical technique in configurational and conformational assignment of chiral compounds are illustrated with significant examples from literature reports within 2003-2008 period. The advantages, as well as inherent limitations of VCD as complementary or competing technique to the classical chiroptical methods are underlined.
引用
收藏
页码：86 / 98
页数：13
相关论文
共 107 条
  • [61] Structural studies on McN-5652-X, a high-affinity ligand for the serotonin transporter in mammalian brain
    Maryanoff, BE
    McComsey, DF
    Dukor, RK
    Nafie, LA
    Freedman, TB
    Cao, XL
    Day, VW
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2003, 11 (11) : 2463 - 2470
  • [62] Application of chiral technology in a pharmaceutical company. Enantiomeric separation and spectroscopic studies of key asymmetric intermediates using a combination of techniques. Phenylglycidols
    McConnell, Oliver
    He, Yanan
    Nogle, Lisa
    Sarkahian, Ani
    [J]. CHIRALITY, 2007, 19 (09) : 716 - 730
  • [63] ALPHA-PHOSPHORYL SULFOXIDES .8. STEREOCHEMISTRY OF ALPHA-CHLORINATION OF ALPHA-PHOSPHORYL SULFOXIDES
    MIKOLAJCZYK, M
    MIDURA, WH
    GRZEJSZCZAK, S
    MONTANARI, F
    CINQUINI, M
    WIECZOREK, MW
    KAROLAKWOJCIECHOWSKA, J
    [J]. TETRAHEDRON, 1994, 50 (27) : 8053 - 8072
  • [64] Mikolajczyk M., 1997, CHIRAL SULFUR REAGEN
  • [65] A structure and an absolute configuration of (+)-alternamin, a new coumarin from Murraya alternans having antidote activity against snake venom
    Min, Hia Myoe
    Aye, Mya
    Taniguchi, Tohru
    Miura, Nobuaki
    Monde, Kenji
    Ohzawa, Kazuhiko
    Nikai, Toshiaki
    Niwa, Masatake
    Takaya, Yoshiaki
    [J]. TETRAHEDRON LETTERS, 2007, 48 (35) : 6155 - 6158
  • [66] An investigation of the absolute configuration of the potent histamine H3 receptor antagonist GT-2331 using vibrational circular dichroism
    Minick, Douglas J.
    Copley, Royston C. B.
    Szewczyk, Jerzy R.
    Rutkowske, Randy D.
    Miller, Luke A.
    [J]. CHIRALITY, 2007, 19 (09) : 731 - 740
  • [67] Synthesis, resolution, and VCD analysis of an enantiopure diazaoxatricornan derivative
    Mobian, Pierre
    Nicolas, Cyril
    Francotte, Eric
    Burgi, Thomas
    Lacour, Jerome
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (20) : 6507 - 6514
  • [68] Absolute configurations of brominated sesquiterpenes determined by vibrational circular dichroism
    Monde, K
    Taniguchi, T
    Miura, N
    Vairappan, CS
    Suzuki, M
    [J]. CHIRALITY, 2006, 18 (05) : 335 - 339
  • [69] Absolute configurations of endoperoxides determined by vibrational circular dichroism (VCD)
    Monde, Kenji
    Taniguchi, Tohru
    Miura, Nobuaki
    Vairappan, Charles S.
    Suzuki, Minoru
    [J]. TETRAHEDRON LETTERS, 2006, 47 (26) : 4389 - 4392
  • [70] Quantum chemical study on the circular dichroism spectra and specific rotation of donor-acceptor cyclophanes
    Mori, Tadashi
    Inoue, Yoshihisa
    Grimme, Stefan
    [J]. JOURNAL OF PHYSICAL CHEMISTRY A, 2007, 111 (32) : 7995 - 8006
234567891011