Advances in radiotherapy for brain metastases

被引：6
作者：
Gondi, Vinai [1 ]
Meyer, Jacquelyn [2 ]
Shih, Helen A. [3 ]
机构：
[1] Northwestern Med Canc Ctr Warrenville & Proton Ct, 4405 Weaver Pkwy, Warrenville, IL 60555 USA
[2] Univ Wisconsin, Madison, WI USA
[3] Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02114 USA
来源：
NEURO-ONCOLOGY ADVANCES | 2021年 / 3卷
关键词：
brain metastases; modern management; radiotherapy; stereotactic radiosurgery; whole-brain radiotherapy; POSTOPERATIVE STEREOTACTIC RADIOSURGERY; RADIATION-THERAPY; HIPPOCAMPAL AVOIDANCE; SURGICAL RESECTION; SINGLE METASTASES; DENTATE GYRUS; IRRADIATION; MEMANTINE; TRIAL; PHASE-3;
D O I：
10.1093/noajnl/vdab126
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
As novel systemic therapies yield improved survival in metastatic cancer patients, the frequency of brain metastases continues to increase. Over the years, management strategies have continued to evolve. Historically, stereotactic radiosurgery has been used as a boost to whole-brain radiotherapy (WBRT) but is increasingly being used as a replacement for WBRT. Given its capacity to treat both macro- and micro-metastases in the brain, WBRT has been an important management strategy for years, and recent research has identified technologic and pharmacologic approaches to delivering WBRT more safely. In this review, we outline the current landscape of radiotherapeutic treatment options and discuss approaches to integrating radiotherapy advances in the contemporary management of brain metastases.
引用
收藏
页码：V26 / V34
页数：9
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